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Title: Cytochrome P4501A1 polymorphism is associated with susceptibility to acute lymphoblastic leukemia in adult Mexican patients
Author: Gallegos-Arreola, M.P.
Batista-Gonzalez, C.M.
Delgado-Lamas, J.L.
Figuera, L.E.
Puebla-Perez, A.M.
Arnaud-Lopez, L.
Peralta-Leal, V.
Ramirez-Jirano, L.J.
Zuniga-Gonzalez, G.M.
Issue Date: 2004
Abstract: We studied the role of cytochrome P4501A1 (CYP1A1 Val/Val) genotypes in the etiology of acute lymphoblastic leukemia (ALL) in adult Mexican patients. Distributions of CYP1A1 Val/Val genotypes in peripheral blood DNA samples from 136 healthy controls and 136 adult patients with ALL were evaluated. There was an increased frequency of the CYP1A1 Val/Val genotype among ALL patients, showing a significant association between this genotype and the risk of developing ALL. © 2004 Elsevier Inc. All rights reserved.
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