Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/66270
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dc.contributor.authorOrtuno Sahagun, D.
dc.contributor.authorMarquez-Aguirre, A.L.
dc.contributor.authorQuintero-Fabian, S.
dc.contributor.authorLopez-Roa, R.I.
dc.contributor.authorRojas-Mayorquin, A.E.
dc.date.accessioned2015-11-19T18:51:09Z-
dc.date.available2015-11-19T18:51:09Z-
dc.date.issued2012
dc.identifier.urihttp://hdl.handle.net/20.500.12104/66270-
dc.description.abstractA direct correlation between adequate nutrition and health is a universally accepted truth. The Western lifestyle, with a high intake of simple sugars, saturated fat, and physical inactivity, promotes pathologic conditions. The main adverse consequences range from cardiovascular disease, type 2 diabetes, and metabolic syndrome to several cancers. Dietary components influence tissue homeostasis in multiple ways and many different functional foods have been associated with various health benefits when consumed. Natural products are an important and promising source for drug discovery. Many anti-inflammatory natural products activate peroxisome proliferator-activated receptors (PPAR); therefore, compounds that activate or modulate PPAR-gamma (PPAR-γ) may help to fight all of these pathological conditions. Consequently, the discovery and optimization of novel PPAR-γ agonists and modulators that would display reduced side effects is of great interest. In this paper, we present some of the main naturally derived products studied that exert an influence on metabolism through the activation or modulation of PPAR-γ, and we also present PPAR-γ-related diseases that can be complementarily treated with nutraceutics from functional foods. © 2012 D. Ortuño Sahagún et al.
dc.titleModulation of PPAR-γ by nutraceutics as complementary treatment for obesity-related disorders and inflammatory diseases
dc.typeReview
dc.identifier.doi10.1155/2012/318613
dc.relation.ispartofjournalPPAR Research
dc.relation.ispartofvolume2012
dc.relation.ispartofpage318613
dc.contributor.affiliationOrtuño Sahagún, D., Laboratorio de Desarrollo y Regeneración Neural, Instituto de Neurobiología, Universidad de Guadalajara, camino Ing. R. Padilla Sánchez 2100, Las Agujas, 44600 Zapopan JAL, Mexico; Márquez-Aguirre, A.L., Unidad de Biotecnología Médica y Farmacéutica, Centro de Investigacion y Asistencia en Tecnologia y Diseno Del Estado de Jalisco A.C., 44270 Guadalajara, JAL, Mexico; Quintero-Fabián, S., Laboratorio de Desarrollo y Regeneración Neural, Instituto de Neurobiología, Universidad de Guadalajara, camino Ing. R. Padilla Sánchez 2100, Las Agujas, 44600 Zapopan JAL, Mexico, Departamento de Farmacobiología, CUCEI, Universidad de Guadalajara, Boulevard Marcelino García Barragán, 44430 Tlaquepaque, JAL, Mexico; López-Roa, R.I., Departamento de Farmacobiología, CUCEI, Universidad de Guadalajara, Boulevard Marcelino García Barragán, 44430 Tlaquepaque, JAL, Mexico; Rojas-Mayorquín, A.E., Departamento de Ciencias Ambientales, Instituto de Neurociencias, Universidad de Guadalajara, 45100 JAL, Mexico, Departamento de Investigación Básica, Instituto Nacional de Geriatría (INGER), Periférico Sur No. 2767, Delegacion Magdalena Contreras 10200, Mexico DF, Mexico
dc.relation.isReferencedByScopus
dc.relation.isReferencedByMEDLINE
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84871847564&partnerID=40&md5=81613e31b37e5f2bb0303b4cbae44677
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=23251142
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