Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/65454
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dc.contributor.authorRosales-Cobtes, M.
dc.contributor.authorPeregrina-Sandoval, J.
dc.contributor.authorBanuelos-Pineda, J.
dc.contributor.authorSarabia-Estrada, R.
dc.contributor.authorGomez-Rodiles, C.C.
dc.contributor.authorAlbarran-Rodriguez, E.
dc.contributor.authorZaitseva, G.P.
dc.contributor.authorPita-Lopez, M.L.
dc.date.accessioned2015-11-19T18:50:23Z-
dc.date.available2015-11-19T18:50:23Z-
dc.date.issued2003
dc.identifier.urihttp://hdl.handle.net/20.500.12104/65454-
dc.description.abstractThis study demonstrated that when the regeneration of the axotomized sciatic nerve is induced through tubulization with chitosan, this biomaterial does not induce immunostimulation or immunodepression in the dog. Canine females were distributed among three groups: an intact control group which was only isolated, an axotomized control group, and an axotomized group which was tubulized with 3% chitosan prostheses. In vitro culture and phagocytosis tests, as well as IgG and IgM serum concentrations, were determined in peripheral blood on days 0, 15, 30 and 60. The results showed that chitosan implants did not importantly affect the immune response.
dc.titleImmunological study of a chitosan prosthesis in the sciatic nerve regeneration of the axotomized dog
dc.typeArticle
dc.identifier.doi10.1177/0885328203018001002
dc.relation.ispartofjournalJournal of Biomaterials Applications
dc.relation.ispartofvolume18
dc.relation.ispartofissue1
dc.relation.ispartofpage15
dc.relation.ispartofpage23
dc.subject.keywordBiomaterial; Cellular immune response; Chitosan; Humoral immune response; Immunological study; Sciatic nerve
dc.contributor.affiliationRosales-Cobtés, M., Div. Medicina Veterinaria, Dept. Neuromorfoloǵia, UdeG, Guadalajara, Mexico; Peregrina-Sandoval, J., Div. Medicina Veterinaria, Dept. Neuromorfoloǵia, UdeG, Guadalajara, Mexico; Bañuelos-Pineda, J., Div. Medicina Veterinaria, Dept. Neuromorfoloǵia, UdeG, Guadalajara, Mexico; Sarabia-Estrada, R., Div. Medicina Veterinaria, Dept. Neuromorfoloǵia, UdeG, Guadalajara, Mexico; Gómez-Rodiles, C.C., Div. Medicina Veterinaria, Dept. Neuromorfoloǵia, UdeG, Guadalajara, Mexico; Albarrán-Rodríguez, E., Div. Medicina Veterinaria, Dept. Neuromorfoloǵia, UdeG, Guadalajara, Mexico; Zaitseva, G.P., Div. Ciencias Biológicas, Dpto. Biología Celular, UdeG, Guadalajara, Mexico; Pita-López, M.L., Div. Ciencias Biológicas, Dpto. Biología Celular, UdeG, Guadalajara, Mexico
dc.relation.isReferencedByScopus
dc.relation.isReferencedByWOS
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-0038389520&partnerID=40&md5=7a4dfdd1cf57b2bed46c82d821deb39d
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