Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/65421
Title: Idiopathic hypertrophic cranial pachymeningitis successfully treated with weekly subcutaneous methotrexate
Author: Ruiz-Sandoval, J.L.
Bernard-Medina, G.
Ramos-Gomez, E.J.
Romero-Vargas, S.
Gutierrez-Urena, S.
Gonzalez-Cornejo, S.
Chiquete, E.
Issue Date: 2006
Abstract: Idiopathic hypertrophic cranial pachymeningitis is a very infrequent disorder. Adequate management is still a matter of debate. We describe the use of low-dose pulse methotrexate in treating a 63-year-old woman with idiopathic hypertrophic cranial pachymeningitis. A weekly scheme with subcutaneous methotrexate was tried. Clinical improvement occurred in one week. Total remission of the clinical and neuro-imaging abnormalities was evident 6 months later, with minimal side effects. The patient is in complete remission after one year of follow-up without treatment. Hence, low-dose weekly subcutaneous methotrexate may be safe and effective in inducing complete and sustained remission of this condition. The experience with subcutaneous methotrexate to treat this entity has never been reported. © Springer-Verlag 2006.
URI: http://hdl.handle.net/20.500.12104/65421
Appears in Collections:Producción científica UdeG (prueba)

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