Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/64281
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dc.contributor.authorIbarra-Hurtado, T.R.
dc.contributor.authorNuno-Guzman, C.M.
dc.contributor.authorMiranda-Diaz, A.G.
dc.contributor.authorTroyo-Sanroman, R.
dc.contributor.authorNavarro-Ibarra, R.
dc.contributor.authorBravo-Cuellar, L.
dc.date.accessioned2015-11-19T18:49:14Z-
dc.date.available2015-11-19T18:49:14Z-
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/20.500.12104/64281-
dc.description.abstractPurpose: Abdominal wall hernia secondary to open abdomen management represents a surgical challenge. The hernia worsens due to lateral muscle retraction. Our objective was to evaluate if Botulinum Toxin Type A (BTA) application in lateral abdominal wall muscles modifies its thickness and length.Methods: A clinical trial of male trauma patients with hernia secondary to open abdomen management was performed from January 2009 to July 2011. Thickness and length of lateral abdominal muscles were measured by a basal Computed Tomography and 1 month after BTA application. A dosage of 250 units of BTA was applied at five points at each side between the external and internal oblique muscles under ultrasonographic guidance. Statistical analysis for differences between basal and after BTA application measures was performed by a paired Student’s t test (significance: p < 0.05).Results: Seventeen male patients with a mean age of 35 years were included. There were muscle measure modifications in all the patients. Left muscle thickness: mean reduction of 1 ± 0.55 cm (p < 0.001). Right muscle thickness: mean reduction of 1.00 ± 0.49 cm (p < 0.001). Left muscle length: mean increase of 2.44 ± 1.22 cm (p < 0.001). Right muscle length: mean increase of 2.59 ± 1.38 cm (p < 0.001). No complications secondary to BTA or recurrences at mean follow-up of 49 months were observed.Conclusions: BTA application in lateral abdominal muscles decreases its thickness and increases its length in abdominal wall hernia patients secondary to open abdomen management. © 2014, Springer-Verlag France.
dc.titleEffect of botulinum toxin type A in lateral abdominal wall muscles thickness and length of patients with midline incisional hernia secondary to open abdomen management
dc.typeArticle
dc.identifier.doi10.1007/s10029-014-1280-2
dc.relation.ispartofjournalHernia
dc.relation.ispartofvolume18
dc.relation.ispartofissue5
dc.relation.ispartofpage647
dc.relation.ispartofpage652
dc.subject.keywordAbdominal wall; Botulinum toxin type A; Incisional hernia; Open abdomen management
dc.contributor.affiliationIbarra-Hurtado, T.R., Department of Trauma Surgery, Antiguo Hospital Civil de Guadalajara “Fray Antonio Alcalde”, Calle Hospital 278, Col. El RetiroGuadalajara, Jalisco, Mexico, Pólvora 495, Interior 41. Col. Lagos del CountryZapopan, Jalisco, Mexico; Nuño-Guzmán, C.M., Department of General Surgery, Antiguo Hospital Civil de Guadalajara “Fray Antonio Alcalde”, Calle Hospital 278, Col. El RetiroGuadalajara, Jalisco, Mexico; Miranda-Díaz, A.G., Department of Physiology, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Col. IndependenciaGuadalajara, Jalisco, Mexico; Troyo-Sanromán, R., Department of Physiology, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Col. IndependenciaGuadalajara, Jalisco, Mexico; Navarro-Ibarra, R., Department of Anesthesiology, Antiguo Hospital Civil de Guadalajara “Fray Antonio Alcalde”, Calle Hospital 278, Col. El RetiroGuadalajara, Jalisco, Mexico; Bravo-Cuéllar, L., Department of Trauma Surgery, Antiguo Hospital Civil de Guadalajara “Fray Antonio Alcalde”, Calle Hospital 278, Col. El RetiroGuadalajara, Jalisco, Mexico
dc.relation.isReferencedByScopus
dc.relation.isReferencedByWOS
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84919451310&partnerID=40&md5=0a95422d5ff4653b2a1daca73ece0662
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