Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/45483
Title: Tumor necrosis factor receptor 2 M196R polymorphism in rheumatoid arthritis and osteoarthritis: Relationship with sTNFR2 levels and clinical features
Author: Camps, I.
Muhl, S.
Camps, E.
Quinones-Galvan, J.G.
Flores, M.
Issue Date: 2014
Abstract: The simultaneous ablation of silicon and titanium targets in a nitrogen atmosphere was performed in order to obtain the ternary compound TiSiN. The study showed that the plasma density played an important role in determining the composition and properties of the deposited thin films. The plasma parameters were measured using a planar Langmuir probe. The laser fluence applied to the silicon target was varied and this changed the silicon plasma density. The results demonstrated that the deposition rate and the silicon content in the films strongly depended on the plasma density. The composition measurements showed that the silicon content changed from 6 to 29at.% when the plasma density was increased from 1 1019m-3 to 1 1020m-3. The silicon ion energy was fixed at ~160eV. In order to determine the hardness, friction coefficient, wear resistance and adhesion of the coatings, the TiSiN films were deposited onto nitrided stainless steel substrates at low temperature (200°C) and a working pressure of 1.33Pa (Ar/N2 60/40). The overall results showed that the film hardness varied between 24 and 34GPa, the friction coefficient (in air) from 0.55 to 0.58 with a wear rate as low as 1.2 10-6mm3/Nm and the critical load of adhesion, measured by scratch testing, was between 30 and 64N. " 2014 Elsevier B.V.",,,,,,"10.1016/j.surfcoat.2013.12.064",,,"http://hdl.handle.net/20.500.12104/45483","http://www.scopus.com/inward/record.url?eid=2-s2.0-84906318978&partnerID=40&md5=f74ddba30aebc933ad83d95236ba328a",,,,,,,,"Surface and Coatings Technology",,"74
78",,"255",,"Scopus
WOS",,,,,,"Laser ablation; Thin films; TiSiN; Tribology",,,,,,"Tribological properties of TiSiN thin films deposited by laser ablation",,"Article" "47225","123456789/35008",,"Castellanos-Guzman, A.G., Laboratorio de Investigación en Materiales, DIP-CUCEI, Universidad de Guadalajara, Apdo, Postal 2-638, CP44281 Guadalajara Jal, Mexico; Czank, M., Institut for Geowissenschaften, Crystallography, Universityt Kiel, Olshausenstrasse 40, D-24098 Kiel, Germany",,"Castellanos-Guzman, A.G.
Czank, M.",,"2003",,"The ferroic domain structure of Co 3 B 7 O 13 Cl boracite single crystals has been investigated by transmission electron microscopy (TEM) in conjunction with polarised-light microscopy (PLM). TEM studies revealed the existence of microtwins lamellae with (001) as twin plane.",,,,,,"10.1080/00150190390222231",,,"http://hdl.handle.net/20.500.12104/45446","http://www.scopus.com/inward/record.url?eid=2-s2.0-33746297659&partnerID=40&md5=cb7fbf9e6f9f45ca1a7afd54c568c06f",,,,,,,,"Ferroelectrics",,"15
22",,"290",,"Scopus
WOS",,,,,,"Boracites; Domains; Ferroelasticity; Ferroelectricity; Polarized light microscopy and transmission electron microscopy",,,,,,"Transmission electron and optical microscopy of the domain structure in ferroic Co3B7O13Cl boracite",,"Conference Paper" "47233","123456789/35008",,"Ramos-Zúñiga, R., Department of Neurosciences, Ctro. Univ. de Ciencias de la Salud, University of Guadalajara, Guadalajara, Jalisco, Mexico, Department of Neurosurgery, Hospital V. Gomez Farias, Inst. de Seguridad y Serv. Sociales, Guadalajara, Jalisco, Mexico, Victoria #1531, Col. Providencia, CP: 44630 Cuadalajara, Jalisco, Mexico; Velázquez, H., Department of Neurosciences, Ctro. Univ. de Ciencias de la Salud, University of Guadalajara, Guadalajara, Jalisco, Mexico, Department of Neurosurgery, Hospital V. Gomez Farias, Inst. de Seguridad y Serv. Sociales, Guadalajara, Jalisco, Mexico; Barajas, M.A., Department of Neurosciences, Ctro. Univ. de Ciencias de la Salud, University of Guadalajara, Guadalajara, Jalisco, Mexico; López, R., Department of Neurosurgery, Hospital V. Gomez Farias, Inst. de Seguridad y Serv. Sociales, Guadalajara, Jalisco, Mexico; Sánchez, E., Department of Neurosurgery, Hospital V. Gomez Farias, Inst. de Seguridad y Serv. Sociales, Guadalajara, Jalisco, Mexico; Trejo, S., Department of Anesthesiology, Hospital V. Gomez Farias, Inst. de Seguridad y Serv. Sociales, Guadalajara, Jalisco, Mexico; Batjer, H.H.; Marchese, M.J.; Solomon, R.A.; Barrow, D.L.",,"Ramos-Zuniga, R.
Velazquez, H.
Barajas, M.A.
Lopez, R.
Sanchez, E.
Trejo, S.
Batjer, H.H.
Marchese, M.J.
Solomon, R.A.
Barrow, D.L.",,"2002",,"OBJECTIVE: The trans-supraorbital approach has the advantage of combining the keyhole principle with cranial base surgery. The anatomic fields that can be visualized with the use of this procedure have been demonstrated in cadavers, and the advantages and potential surgical applications of this procedure are described in this report. This article is the first to describe a group of intracranial supratentorial aneurysms. METHODS: We used the trans-supraorbital approach in 22 cases of supratentorial aneurysms. In this technique, an incision is made through the eyebrow, then a 3.5-cm craniotomy is performed with en bloc extension to the orbital arch, complemented by different drilling extensions of the orbital roof according to the surgical objective. We describe the anatomic details of the experimental work as well as the clinical results. RESULTS: The trans-supraorbital technique offers an unlimited wide exposure of neurovascular structures in this microsurgical corridor. The craniotomy extension allows greater exposure than the conventional keyhole supraorbital approach, which makes the technique safe for the patient and comfortable for the surgeon. All patient outcomes were successful; no serious complications from the surgical technique occurred. Our success was achieved through better microscopic illumination in the deep field and by gaining access to the complete supratentorial vascular territory with minimal cerebral retraction and an acceptable cosmetic result. CONCLUSION: The trans-supraorbital approach is effective for gaining access to and treating supratentorial aneurysms. Also, the microsurgical field is more convenient in microscope-assisted surgery because total reliance on the endoscope is not required, and minimal brain retraction is needed. This modification of the keyhole procedure also provides multiple surgical options in this microsurgical corridor, using the principles of minimal invasiveness in cranial base surgery.",,,,,,"10.1097/00006123-200207000-00019",,,"http://hdl.handle.net/20.500.12104/45454","WOS",,,,,,"1",,"Neurosurgery",,"125
131",,"51",,"Scopus",,,,,,"Cerebral aneurysms; Endoscope-assisted microneurosurgery; Keyhole surgery; Microanatomy",,,,,,"Trans-supraorbital approach to supratentorial aneurysms",,"Article" "47246","123456789/35008",,"Delgado-Rizo, V., Inst. of Molec. Biology in Medicine, CUCS, Univ. Guadalajara, Apdo. P., 44281 Guadalajara, Jal, Mexico; Salazar, A., Inst. of Molec. Biology in Medicine, CUCS, Univ. Guadalajara, Apdo. P., 44281 Guadalajara, Jal, Mexico; Panduro, A., Inst. of Molec. Biology in Medicine, CUCS, Univ. Guadalajara, Apdo. P., 44281 Guadalajara, Jal, Mexico; Armendáriz-Borunda, J., Inst. of Molec. Biology in Medicine, CUCS, Univ. Guadalajara, Apdo. P., 44281 Guadalajara, Jal, Mexico
Panduro-Cerda, Arturo., Universidad de Guadalajara. Centro Universitario de Ciencias de la Salud",,"Delgado-Rizo, V.
Salazar, A.
Panduro-Cerda, Arturo
Armendariz-Borunda, J.",,"1998",,"The role of transforming growth factor ?1 (TGF-?1) in mediating hepatic inflammation and regeneration after acute liver injury is beginning to be elucidated, yet its in vivo effect on the gene expression of the major pro-inflammatory and antiinflammatory cytokines produced during that process is unknown. Our previous experiments demonstrated that anti-TGF-?-treated animals presented profound histological changes as compared with control animals. Therefore, our hypothesis was that by blocking in vivo TGF-?1 action, with polyclonal anti-TGF-? antibodies, we could monitor by RT-PCR significative alterations on the gene expression of IL-1?, IL-6, TGF-?, TNF-?, IL-4 and IL-10 in liver-regenerated rats after administration of a single CCl4 dosing. Accordingly, we here report a completely different pattern of cytokines gene expression amidst those groups of rats. Pro- inflammatory cytokines gene expression in control animals showed a clear-cut pattern peaking at 1-2 days postinjury and declining thereafter. Interestingly, IL-6 was present in the control animals only between 12 and 24 h after CCl4 dosing. In the experimental animals, TGF-?1 was mainly increased at 4 and 6 days, while IL-6 mRNA was completely absent. IL-l? mRNA expression was also altered in the experimental rats, albeit TNF-? was nearly unaffected. IL-4 was fully absent in control rats, but remarkably expressed in experimental animals throughout the study. IL-10 was also more expressed in experimental animals.",,,,,,"10.1016/S0167-4781(98)00111-0",,,"http://hdl.handle.net/20.500.12104/45467","http://www.scopus.com/inward/record.url?eid=2-s2.0-0032561440&partnerID=40&md5=46ff0bddcfce1e8a0cade01e84135451",,,,,,"1",,"Biochimica et Biophysica Acta - Gene Structure and Expression",,"20
27",,"1442",,"Scopus
WOS",,,,,,"CCl4; Cytokine; Hepatic regeneration; Inflammation; RT-PCR",,,,,,"Treatment with anti-transforming growth factor ? antibodies influences an altered pattern of cytokines gene expression in injured rat liver",,"Article" "47276","123456789/35008",,"Oregón-Romero, E., Ciencias Biomédicas, Orientación en Inmunología, Instituto de Investigacion en Reumatologia Y del Sistema Musculo Esqueletico, Universidad de Guadalajara, S. Mojada No. 950, Col. Independ., 44340 Guadalajara, Jalisco, Mexico; Vázquez-Del Mercado, M., Ciencias Biomédicas, Orientación en Inmunología, Instituto de Investigacion en Reumatologia Y del Sistema Musculo Esqueletico, Universidad de Guadalajara, S. Mojada No. 950, Col. Independ., 44340 Guadalajara, Jalisco, Mexico; Navarro-Hernández, R.E., Ciencias Biomédicas, Orientación en Inmunología, Instituto de Investigacion en Reumatologia Y del Sistema Musculo Esqueletico, Universidad de Guadalajara, S. Mojada No. 950, Col. Independ., 44340 Guadalajara, Jalisco, Mexico; Torres-Carrillo, N., Ciencias Biomédicas, Orientación en Inmunología, Instituto de Investigacion en Reumatologia Y del Sistema Musculo Esqueletico, Universidad de Guadalajara, S. Mojada No. 950, Col. Independ., 44340 Guadalajara, Jalisco, Mexico; Martínez-Bonilla, G., Servicio de Reumatología, Hospital Civil Fray Antonio Alcalde, Hospital No. 278, Col. El Retiro, 44100 Guadalajara, Jalisco, Mexico; Estrada-García, I., Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional, C. y P. de Ayala s/n, Col. S. Tomas, 11340 Mexico D.F., Mexico; Rangel-Villalobos, H., Laboratorio de Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara, Km 3.3 carretera Ocotlan-Tototlan, Ocotlán, Jalisco, Mexico; Muñoz-Valle, J.F., Ciencias Biomédicas, Orientación en Inmunología, Instituto de Investigacion en Reumatologia Y del Sistema Musculo Esqueletico, Universidad de Guadalajara, S. Mojada No. 950, Col. Independ., 44340 Guadalajara, Jalisco, Mexico, Instituto de Investigacion en Reumatologia Y del Sistema Musculo Esqueletico, Centro Universitario de Ciencias de la Salud, Sierra Mojada Street No. 950, 44281 Guadalajara, Jalisco, Mexico",,"Oregon-Romero, E.
Vazquez-Del Mercado, M.
Navarro-Hernandez, R.E.
Torres-Carrillo, N.
Martinez-Bonilla, G.
Estrada-García, I.
Rangel-Villalobos, H.
Munoz-Valle, J.F.",,"2006",,"We investigate the clinical association of tumor necrosis factor receptor 2 (TNFR2) M196R polymorphism with rheumatoid arthritis (RA) and knee osteoarthritis (OA). Acute phase reactants, lipid profile, sTNFR2 levels, disease activity-disability indexes, and TNFR2 M196R polymorphism were analyzed in 50 RA, 50 knee OA patients, and 120 healthy subjects (HS). The M/M genotype frequency was 0.74 (RA), 0.80 (OA), and 0.64 (HS). The M/R genotype frequency was RA (0.26), OA (0.20), and HS (0.29). The R/R genotype was observed only in HS (0.07). The M allele was associated with OA (P = 0.0137, OR = 2.43). Total cholesterol, triglyceride levels, apolipoprotein A-I and B showed significant differences (P < 0.05). The highest sTNFR2 levels were observed in RA and OA (P = 0.001), however M/M and M/R carriers do not correlate with sTNFR2 production. Our findings suggest an association of the M allele with knee OA. In addition, high sTNFR2 levels in RA and OA were found. " 2006 Springer-Verlag.
URI: http://hdl.handle.net/20.500.12104/45497
http://www.scopus.com/inward/record.url?eid=2-s2.0-33750450860&partnerID=40&md5=898c75b8c265a10fbbeb3811c8b70c2c
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