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Title: Topological gravity on plumbed V-cobordisms
Author: Chavez-Delgado, M.E.
Kishi-Sutto, C.V.
Albores De La-Riva, X.N.
Rosales-Cortes, M.
Gamboa-Sanchez, P.
Issue Date: 2014
Abstract: Background: The main postoperative complications after tonsillectomy are due to bleeding, and effective hemostasis may lead to a reduction of overall postoperative morbidity. This study was undertaken to determine the efficacy and safety of a novel kaolin-based hemostatic dressing in tonsillectomy. Methods: A pilot, single-blind, open label study was performed in patients aged 3e20 y with history of chronic or hypertrophic tonsillitis. Cold dissection tonsillectomy (CDT) + ligature was performed by the same surgeon. Hemostasis on each tonsillar fossa was achieved using kaolin-impregnated gauze (KG; study group) or standard surgical cotton gauze (CG; control). Time to complete hemostasis, operative time, intraoperative blood loss, pain score, analgesic use, and return to normal diet and activity were recorded for all children. Results: A total of 230 patients with a mean age of 8.0 y (138 in the study group and 92 in the control group) were included in the study. Both operative time and intraoperative blood loss were significantly reduced in the KG group (P < 0.0001) versus the CG group. At 5 min, 84.8% patients using the KG successfully achieved complete hemostasis versus 34.8% in the CG group where standard gauze controlled bleeding only partially. Results show significantly less pain for the KG group at 6- and 12-h postoperative when compared with the CG group (P < 0.0001). Also, the KG group required less analgesic medications, returned to normal diet and normal activities faster than the CG group (P < 0.01). Conclusions: Preliminary findings show that the KG is effective and safe in managing surgical bleeding after tonsillectomy. In addition to rapid bleeding control, the dressing causes minimal inflammation and pain and allows patients to quickly return to normal activities. This novel dressing is a promising tool for ear, nose and throat surgical hemostasis. " 2014 Elsevier Inc. All rights reserved.",,,,,,"10.1016/j.jss.2014.05.040",,,"","",,,,,,"2",,"Journal of Surgical Research",,"678
MEDLINE",,,,"Index Medicus;Adolescent;Antidiarrheals/ad [Administration & Dosage];Antidiarrheals/ae [Adverse Effects];Bandages;Child;Child, Preschool;Female;Hemostasis, Surgical/mt [Methods];Hemostatics/ad [Administration & Dosage];Hemostatics/ae [Adverse Effects];Humans;Kaolin/ad [Administration & Dosage];Kaolin/ae [Adverse Effects];Male;Pain, Postoperative/pc [Prevention & Control];Pilot Projects;Postoperative Hemorrhage/pc [Prevention & Control];Prospective Studies;Single-Blind Method;Surgical Sponges;Tonsillectomy/mt [Methods];Young Adult",,"Kaolin gauze; Painless tonsillectomy; Surgical bleeding; Tonsil surgery; Topical hemostatic agent",,,,,,"Topic usage of kaolin-impregnated gauze as a hemostatic in tonsillectomy",,"Article" "47176","123456789/35008",,"Efremov, V.N., Mathematics Department, CUCEI, University of Guadalajara, Guadalajara, Mexico; Mitskievich, N.V., Physics Department, CUCEI, University of Guadalajara, Guadalajara, Mexico; Magdaleno, A.M.H., Physics Department, CUCEI, University of Guadalajara, Guadalajara, Mexico; Bautista, R.S., Mathematics Department, CUCEI, University of Guadalajara, Guadalajara, Mexico",,"Efremov, V.N.
Mitskievich, N.V.
Magdaleno, A.M.H.
Bautista, R.S.",,"2005",,"An ensemble of cosmological models based on generalized BF-theory is constructed where the role of vacuum (zero-level) coupling constants is played by topologically invariant rational intersection forms (cosmological-constant matrices) of four-dimensional plumbed V-cobordisms which are interpreted as Euclidean spacetime regions. For these regions describing topology changes, the rational and integer intersection matrices are calculated. A relation is found between the hierarchy of certain elements of these matrices and the hierarchy of coupling constants of the universal (low-energy) interactions. " 2005 IOP Publishing Ltd.
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