Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/45288
Title: The role of FABP2 gene polymorphism in alcoholic cirrhosis
Author: Burlak, G.N.
Klimov, Andrei B.
Issue Date: 2007
Abstract: We numerically study the dynamical excitations in Bose-Einstein condensate (BEC) placed in periodic and quasiperiodic 2D optical lattice (OL). In case of the repulsive mean-field interaction the BEC quantum tunneling leads to a progressive soliton's splitting and generating of secondary solitons, which migrate to closest trapping potential minima. A nontrivial soliton dynamics appears when a series of ?-pulses (phase kicks) are applied to the optical lattice. Such sudden perturbation produces a dynamic redistribution of the secondary solitons, leading to a formation of an artificial solitonic superlattice. Different geometries of OL are analyzed. " 2007 Elsevier B.V. All rights reserved.",,,,,,"10.1016/j.physleta.2007.05.012",,,"http://hdl.handle.net/20.500.12104/45288","http://www.scopus.com/inward/record.url?eid=2-s2.0-34548614233&partnerID=40&md5=0c641f9275a894f74af2cfd85692d61c",,,,,,"05-jun",,"Physics Letters, Section A: General, Atomic and Solid State Physics",,"510
517",,"369",,"Scopus
WOS",,,,,,,,,,,,"The solitons redistribution in Bose-Einstein condensate in quasiperiodic optical lattice",,"Article" "47046","123456789/35008",,"Salguero, M.L., Department of Molecular Biology, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, P.O. Box 2-500, Guadalajara, 44280 Jalisco, Mexico, Institute of Molecular Biology in Medicine, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico; Leon, R.E., Department of Molecular Biology, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, P.O. Box 2-500, Guadalajara, 44280 Jalisco, Mexico, Institute of Molecular Biology in Medicine, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico; Santos, A., Department of Molecular Biology, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, P.O. Box 2-500, Guadalajara, 44280 Jalisco, Mexico, Institute of Molecular Biology in Medicine, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico, Institute of Ophthalmology and Visual Sciences, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico; Roman, S., Department of Molecular Biology, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, P.O. Box 2-500, Guadalajara, 44280 Jalisco, Mexico, Institute of Molecular Biology in Medicine, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico; Segura-Ortega, J.E., Department of Molecular Biology, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, P.O. Box 2-500, Guadalajara, 44280 Jalisco, Mexico, Institute of Molecular Biology in Medicine, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico; Panduro, A., Department of Molecular Biology, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, P.O. Box 2-500, Guadalajara, 44280 Jalisco, Mexico, Institute of Molecular Biology in Medicine, University of Guadalajara, Sierra Mojada 950, Guadalajara, 44340 Jalisco, Mexico
Panduro-Cerda, Arturo., Universidad de Guadalajara. Centro Universitario de Ciencias de la Salud",,"Salguero, M.L.
Leon, R.E.
Santos, A.
Roman, S.
Segura-Ortega, J.E.
Panduro-Cerda, Arturo",,"2005",,"Hypertriglyceridemia and dietary lipids have been suggested to modulate the severity of alcoholic liver disease and the progression to alcoholic cirrhosis (AC). The intestinal fatty acid binding protein (IFABP) is the main transporter of dietary fatty acids into the enterocyte and has a genetic polymorphism, FABP2 A54T that has been associated with hypertriglyceridemia. We determined the frequency of the FABP2 gene polymorphism using PCR-RFLP and measured serum triglycerides, HDL, LDL, total lipids and cholesterol in 67 patients with AC and in 124 unrelated healthy individuals. Frequencies of genotypes and alleles were similar between the two groups. The healthy subjects, who were homozygous for the Thr54 genotype had significantly higher mean triglyceride serum concentrations than those homozygous for the Ala54 genotype (P < 0.05). However, AC patients who were homozygous for the Thr54 genotype, had lower mean triglyceride serum concentrations (P < 0.01), and had a significantly longer period of continued alcohol abuse prior to the diagnosis of liver cirrhosis compared to the AC patients homozygous for the Ala54 genotype (P < 0.05). Our data suggests that the polymorphism Thr54 of the FABP2 gene is associated with a later onset of AC in the lower economic status Mexican population studied. " 2005 Elsevier Ireland Ltd. All rights reserved.
URI: http://hdl.handle.net/20.500.12104/45267
http://www.scopus.com/inward/record.url?eid=2-s2.0-29144535770&partnerID=40&md5=796f8bf9dd35a50982bd56041bdaf204
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