Please use this identifier to cite or link to this item:
Title: The experience of miners relocated to alternative positions due to silicosis in the Andean of CODELCO, Chile, 2010
Author: Hernandez-Ojeda, J.
Cardona-Munoz, E.G.
Roman-Pintos, L.M.
Troyo-Sanroman, R.
Ortiz-Lazareno, P.C.
Cardenas-Meza, M.A.
Pascoe-Gonzalez, S.
Miranda-Diaz, A.G.
Issue Date: 2012
Abstract: Introduction: Diabetic polyneuropathy aetiology is based on oxidative stress generation due to production of reactive oxygen species. Ubiquinone is reduced to ubiquinol and redistributed into lipoproteins, possibly to protect them from oxidation. Aims: To evaluate the impact of oral ubiquinone in diabetic polyneuropathy, and the role of lipid peroxidation (LPO) and nerve growth factor (NGF-?). Methods: We conducted a double-blind, placebo-controlled clinical trial, patients were randomized to ubiquinone (400 mg) or placebo daily for 12 weeks. Main outcomes were clinical scores, nerve conduction studies, LPO, NGF-? and safety. Results: Twenty four patients on experimental group and twenty five on control group met the inclusion criteria (mean age 56 years, 22% male and 78% female, mean evolution of type 2 diabetes mellitus 10.7 years). Significant improvement on experimental vs control group was found in neuropathy symptoms score (from 2.5 ± 0.7 to 1 ± 0.8, p < 0.001), neuropathy impairment score (5.5 ± 4 to 3.1 ± 2.6, p < 0.001), sural sensory nerve amplitude (13.0 ± 6.1 to 15.8 ± 5.1 ?V, p = 0.049), peroneal motor nerve conduction velocity (39.7 ± 5.0 to 47.8 ± 4.9 m/s, p = 0.047), and ulnar motor nerve conduction velocity (48.8 ± 6.8 to 54.5 ± 6.1 m/s, p = 0.046). There was a significant reduction of LPO in subjects treated with ubiquinone vs placebo (16.7 ± 8.6 and 23.2 ± 15.8 nmol/mL, respectively) with p < 0.05, and NGF-? did not change (control 66.5 ± 26.7 vs. experimental 66.8 ± 28.4 pg/mL, p = 0.856). No drug-related adverse reactions were reported. Conclusions: Twelve weeks treatment with ubiquinone improves clinical outcomes and nerve conduction parameters of diabetic polyneuropathy; furthermore, it reduces oxidative stress without significant adverse events. " 2012 Elsevier Inc. All rights reserved.",,,,,,"10.1016/j.jdiacomp.2012.04.004",,,"","",,,,,,"4",,"Journal of Diabetes and its Complications",,"352
MEDLINE",,,,"Index Medicus;Adult;Aged;Aged, 80 and over;Diabetic Neuropathies/dt [Drug Therapy];Diabetic Neuropathies/me [Metabolism];Diabetic Neuropathies/pp [Physiopathology];Double-Blind Method;Female;Humans;Lipid Peroxidation/de [Drug Effects];Lipid Peroxidation/ph [Physiology];Male;Micronutrients/ae [Adverse Effects];Micronutrients/pd [Pharmacology];Micronutrients/tu [Therapeutic Use];Middle Aged;Nerve Growth Factor/me [Metabolism];Neural Conduction/de [Drug Effects];Neural Conduction/ph [Physiology];Oxidative Stress/de [Drug Effects];Oxidative Stress/ph [Physiology];Treatment Outcome;Ubiquinone/ae [Adverse Effects];Ubiquinone/pd [Pharmacology];Ubiquinone/tu [Therapeutic Use]",,"Diabetic polyneuropathy; Nerve conduction; Nerve growth factor; Oxidative stress; Ubiquinone",,,,,,"The effect of ubiquinone in diabetic polyneuropathy: A randomized double-blind placebo-controlled study",,"Article" "46896","123456789/35008",,"Tetreault, D.V., University of Guadalajara, Guadalajara, Mexico",,"Tetreault, D.V.",,"2006",,"This paper analyses the evolution of poverty in Mexico during the second half of the 20th century and points toward correlations between poverty trends and major changes to economic and social policy. Two poverty-measurement methods are used to construct a general vision of the evolution of poverty in Mexico: the poverty-line method and a variation of the unsatisfied-basic-needs method. The analysis based on the poverty-line method indicates that the incidence of poverty in Mexico decreased continuously and considerably during the last part of the import substituting industrialization (ISI) period (1963-1982), but that it has not decreased significantly since economic liberalization began in 1982; there is evidence to suggest that it has increased slightly since then. Alternatively, the analysis of basic need indicators suggests that there has been a constant and uninterrupted improvement in the satisfaction of basic needs in Mexico throughout the second half of the 20th century. However, it also indicates that the rate of satisfying basic needs has decelerated over the past two decades. Taking all of the empirical evidence presented in this paper into consideration, it appears that the social and economic policies put in place by the Mexican government over the past 20 years, have, by and large, been ineffective in reducing poverty.",,,,,,,,,"","",,,,,,"3",,"Canadian Journal of Development Studies",,"309
WOS",,,,,,,,,,,,"The evolution of poverty in late 20th-century Mexico",,"Article" "46915","123456789/35008",,"Ramírez Rodríguez, J.C., Laboratorio de Salud Pública, Facultad de Medicina, Universidad de Guadalajara.; Uribe Vázquez, G., Laboratorio de Salud Pública, Facultad de Medicina, Universidad de Guadalajara.; Gutiérrez De la Torre, N.C., Laboratorio de Salud Pública, Facultad de Medicina, Universidad de Guadalajara.",,"Ramirez Rodriguez, J.C.
Uribe Vazquez, G.
Gutierrez De la Torre, N.C.",,"1991",,"The epidemiological studies on women's health, with relation to their geographical distribution (rural and urban), have focused on the areas of fertility and family planning. This work attempts to open up, to a worldwide level of comprehension, the perspectives of the problems related to women's health. It show the results of an investigation of two population groups of women, one in the rural zone, and the other in the urban zone; both groups were from the state of Jalisco, Mexico. The objectives were: to identify the more frequent health problems occurring in women and to establish the similarities and differences between these two female groups. The information was obtained by means of unique interviews using questionnaires. Sociodemographic variables, housing, and sanitation were studied, as well as a health questionnaire which was divided into apparatus and systems. Better sanitary conditions and more favorable sociodemographic indicators were found among women in the urban zone as opposed to those in the rural zone. The most frequent health problems are, in decreasing order, those located in the nervous, digestive, cardiovascular, and genital-urinary systems. There exists a direct relationship between the frequency of health problems and age. Generally, the women most affected are those in the rural zone. It is difficult to establish comparisons with the health conditions of women in other areas due to lack of research that makes differentiations with regard to sex (in this case, those focusing on women). We consider it of interest to continue with insightful investigations of chronic, degenerative, and deficiency problems, as well as those related to self-attention.",,,,,,,,,"","",,,,,,"2",,"Salud Publica de Mexico",,"155
165",,"33",,"Scopus",,,,,,,,,,,,"The geographical distribution of women's health problems in Jalisco, Mexico [Distribución espacial de la problemática de salud de la mujer en Jalisco, México.]",,"Article" "46903","123456789/35008",,"Hughes, D.P., Department of Zoology, University of Oxford, South Parks Road, OX1 3PS, United Kingdom; Moya-Raygoza, G., Departamento de Botanica y Zoologia, C.U.C.B.A., Universidad de Guadalajara, Km 15.5 carretera G., Jalisco, Mexico; Kathirithamby, J., Department of Zoology, University of Oxford, South Parks Road, OX1 3PS, United Kingdom",,"Hughes, D.P.
Moya-Raygoza, G.
Kathirithamby, J.",,"2003",,"We present the first record of parasitism of Dolichoderus bispinosus nests by Strepsiptera belonging to the family Myrmecolacidae. This becomes only the fourteenth species of ant and the fifth subfamily to be identified as a host to Strepsiptera. Of the three colonies examined all were parasitized. Prevalence of parasitism among adult ants was less than 2% in each case. However, among alate males of one colony, nearly 24% were parasitized. In conjunction with a reanalysis of previously published data we discuss the possibility that ant castes are differentially parasitized by Strepsiptera. We review the natural history of strepsipteran parasitism in ants, effects on host behaviour and incidences of parasitism in the hope of enabling detection of this parasite by myrmecologists.",,,,,,"10.1007/s00040-003-0637-9",,,"","",,,,,,"2",,"Insectes Sociaux",,"148
WOS",,,,,,"Behaviour change; Dolichoderus bispinosus; Myrmecolacidae; Parasitism; Strepsiptera",,,,,,"The first record among Dolichoderinae (Formicidae) of parasitism by Strepsiptera",,"Article" "46889","123456789/35008",,"Prieto-Miranda, S.E., Division of Internal Medicine, Universidad de Guadalajara, Hospital Civil Juan I. Menchaca, Jalisco 44340, Mexico; Esparza-Ceseña, M.J., Department of Emergency Medicine, Hospital General Regional No. 46 IMSS, Guadalajara, Jalisco, Mexico",,"Prieto-Miranda, S.E.
Esparza-Cesena, M.J.",,"2011",,"[No abstract available]",,,,,,"10.1016/j.ajem.2010.03.012",,,"","",,,,,,"2",,"American Journal of Emergency Medicine",,"2440
MEDLINE",,,,"Index Medicus;Adult;Atropine/ad [Administration & Dosage];Cholinesterase Reactivators/tu [Therapeutic Use];Humans;Male;Mexico;Obidoxime Chloride/ad [Administration & Dosage];Organophosphate Poisoning;Poisoning/dt [Drug Therapy];Suicide, Attempted;Time Factors",,,,,,,,"The efficacy of obidoxime 72 hours after intoxication by organophosphates",,"Article" "46909","123456789/35008",,"Zárate-del Valle, P.F., Departamento de Química, Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Ap. Postal 4-021, 44410 Guadalajara, Jalisco, Mexico; Simoneit, B.R.T., Environmental and Petroleum Geochemistry Group, College of Oceanic and Atmospheric Sciences, Oregon State University, Corvallis, OR 97331-5503, United States",,"Zarate-del Valle, P.F.
Simoneit, B.R.T.",,"2005",,"Lake Chapala, located in the Citala Rift in western Mexico, is characterized by its active and fossil geothermal activity, which includes terrestrial and sublacustrine hot springs, alteration halos, carbonated sinter deposits and mud volcanoes. Sub-lacustrine hot springs and asphalt emanations that constitute islets coexist in the lake. Oil generated in geothermic zones has an hydrothermal origin because circulating hot water generates both thermic alteration of organic matter and mass transference. For this reason, this oil is named hydrothermal petroleum (HP). Analyses by gas chromatography coupled to mass spectrometry (GC-MS) of the HP from Lake Chapala show that it consists of mature biomarkers and an unresolved complex mixture of branched and cyclic hydrocarbons (UCM). The mature biomarkers, derivated from lacustrine microbiota, consist mainly of 17?(H),21?(-H)-hopanes from C27 to C34 (no C28); gammacerane, tricyclic terpanes (C20-C26, no C22); carotane and its cracking products; C28 and C29 steranes and drimanes (C14-C16). The hydrothermal petroleum of the Chapala Lake does not contain polycyclic aromatic hydrocarbons (PAH) nor n-alkanes. The composition of this HP does not fit with conventional biodegraded petroleum residues. The absence of n-alkanes and isoprenoids and presence of UCM, mature hopanes, steranes and carotenoid biomarkers are consistent with rapid hydrothermal oil generation, similar to hydrothermal petroleum from the East African Rift. We propose that the HP from Lake Chapala was generated rapidly from lacustrine organic matter at temperatures below that required for hydrothermal cracking of alkanes from kerogen (250 °C). The hydrothermal petroleum of Lake Chapala was forced by tectonic activity to the lake bed, from a depth estimated in 300-500 m, where the sediments have 14C ages &gt;40 ka. The bulk carbon of the HP of Lake Chapala has a mean ?13CPDB of -21.4 which is a typical value for lacustrine organic matter. The occurrence of hydrothermal petroleum in continental rift systems is now well understood and should be included as a target in exploration for future energy resources in such regions.",,,,,,,,,"","",,,,,,"3",,"Revista Mexicana de Ciencias Geologicas",,"358
WOS",,,,,,"Citala Rift; Hopanes; Hydrothermal petroleum; Lake Chapala; Mature biomarkers; Mexico; Steranes",,,,,,"The generation of hydrothermal oil in sediments of the Chapala Lake, and its relation with the geothermal activity in the Citala rift, Jalisco State, Mexico [La generación de petróleo hidrotermal en sedimentos del Lago Chapala y su relación con la actividad geotérmica del rift Citala en el estado de Jalisco, México]",,"Article" "46881","123456789/35008",,"Favari Perozzi, L., Secc. Externa de Farmacología, CINVESTAV-IPN, Apdo. Postal 14-740, México 07300 D.F., Mexico; Madrigal Ortiz, M., Universidad de Guadalajara, Av. Juárez 976, Guadalajara, Jalisco, Mexico; López López, E., Lab. de Ictiologia y Limnologia, Esc. Nac. de Cie. Biológicas, Carpio y Plan de Ayala, Col. Sto. Tomás, México 11341 D.F., Mexico",,"Favari Perozzi, L.
Madrigal Ortiz, M.
Lopez Lopez, E.",,"2003",,"The discharge of pollutants by industries represents a serious water contamination problem because the contaminants reduce the quality of freshwater and are hazards to the fish population. The Ameca river, located in the Pacific slope of western México is characterized by the presence of springs and a reservoir (De La Vega reservoir). This reservoir receives sewage from the sugar industry. The measurable biological response of an organism to environmental contamination has been termed a biomarker response. The aim of the present study was to investigate the physicochemical characteristics of De La Vega water and the toxic effect of this water. Bioassays were performed in Xiphophorus helleri to determine the effects of a short-term exposure (96 h) to water of De La Vega reservoir on two biomarkers: acetylcholinesterase (AchE) and lipid peroxidation (LP). After acclimatization, the fish were divided into three groups and each group (n=8) was exposed to water of each site, N, C, and S, respectively and the control group (n=8) was maintained in reconditioned water that served as control. In the reservoir there was possible to detect marked fluctuations in the physicochemical factors both with vertical gradients and seasonal fluctuations as occurred with dissolved oxygen, conductivity, turbidity, nitrates and nitrites, on site S. Acetylcholinesterase activity was inhibited in the liver and muscle of exposed fish. There was a 86, 88 and 89 % inhibition of AchE activity in the liver, at N, C and S sites, respectively, after 96 h exposure to reservoir waters compared to control values but the highest AchE inhibition was observed in muscle. Fish exposed to reservoir water also demonstrated a significant increase in LP measured as the amount of TBARS as compared to controls. Water treatment led to 1.5, 2.5 and 4 fold in increase in LP liver and in muscle 2, 1.5 and 3.5 fold corresponding to N, C and S, respectively. Also, the conjugated dienes showed an increase. The water exposure caused a 100 % increase in the level of conjugated dienes in the liver and muscle homogenates. The results reported here indicate that fish subjected to a exposure of combined contaminants of De La Vega water are vulnerable to the toxic effect of them. Although X. helleri is a tolerant species, exposure to levels of pollutants may lead to the impairment of the reproductive activities and changes in either the population size and structure of this species.",,,,,,,,,"","",,,,,,"3",,"Revista Internacional de Contaminacion Ambiental",,"145
155",,"19",,"Scopus",,,,,,"Biomarkers; Contamination; Fish; Organophosphorus insecticides; Reservoir; Sugar industry",,,,,,"The effect of water from de la Vega reservoir on lipoperoxidation and acetylcholinesterase levels in liver and muscle of Xiphophorus helleri [Efecto del agua del embalse de la vega en la lipoperoxidación y los niveles de la acetilcolinesterasa en el hígado y el másculo de Xiphophorus helleri]",,"Article" "46930","123456789/35008",,"García, G.G., Department of Nephrology Service, Hospital Civil de Guadalajara, University of Guadalajara Health Sciences Center (CUCS)Hospital, Guadalajara, Jalisco, Mexico; Harden, P., Oxford Kidney Unit, Oxford Transplant Centre, Churchill Hospital, Oxford, United Kingdom; Chapman, J., Centre for Transplant and Renal Research, Westmead Millennium Institute, Sydney University, Westmead Hospital, Sydney, NSW, Australia",,"García, G.G.
Harden, P.
Chapman, J.",,"2012",,"[No abstract available]",,,,,,"10.1053/j.ackd.2012.02.013",,,"","",,,,,,"2",,"Advances in Chronic Kidney Disease",,"53
WOS",,,,,,,,,,,,"The Global Role of Kidney Transplantation",,"Editorial" "46897","123456789/35008",,"Delgado, D., Occupational Health Unit, Clínica Río Blanco, PO Box: 253, Avenida Santa Maria 777, Villa Minera Andina, Los-Andes, Chile; De Los Angeles Aguilera, M., Institute of Investigation in Occupational Health, University of Guadalajara, Guadalajara, Mexico; Delgado, F., School of Medicine, University Laica Eloy Alfaro of Manabí, Manta, Ecuador; Rug, A., Medical Specialty Center Río Blanco, Los-Andes, Chile",,"Delgado, D.
De Los Angeles Aguilera, M.
Delgado, F.
Rug, A.",,"2012",,"Objectives: To understand the personal experiences of mine workers that have experienced job relocation due to silicosis at the Andina Division of Corporación Nacional del Cobre (CODELCO), Chile. The purpose of the study was to provide useful information for the development of new local, business and public policies for the care of workers with silicosis. Methods: A qualitative study based on a practical case study of 5 workers. The information was collected by means of structured individual interviews. The method of analysis was phenomenology. Results: The corporal axis was the most commented upon. It included awareness of the illness, body pains, fatigue, and antagonistic mood disorders (sadness, or the difficulty in finding meaning in life). As far as personal relationships, there was evidence of strong relationships with family, coworkers and friends, as well as extended family. Over all, the experience of relocation was positive with periods of impatience and uncertainty. The job reassignment provided a new and pleasant context for the relocated workers and in the process improved their perception of their quality of life. Conclusions: A multidisciplinary team should attend mine workers relocated because of silicosis by addressing the mental and physical aspects of their disease, along with the integral participation of close family members. It is suggested that this investigation be maintain over time to record the personal experiences in the medium-term, adding new cases with the intention of shedding more light on the phenomenon being studied. As a preventive measure, continual workshops are needed on the proper use of respiratory protection in addition, a group of monitors is required. Copyright " 2012 by Safety and Health at Work (SH@W).
Appears in Collections:Producción científica UdeG

Files in This Item:
There are no files associated with this item.

Items in RIUdeG are protected by copyright, with all rights reserved, unless otherwise indicated.