Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/42411
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dc.contributor.authorRuiz-Sandoval, J.L.
dc.contributor.authorChiquete, E.
dc.contributor.authorNavarro-Bonnet, J.
dc.contributor.authorOchoa-Guzman, A.
dc.contributor.authorArauz-Gongora, A.
dc.contributor.authorBarinagarrementeria, F.
dc.contributor.authorCantu, C.
dc.date.accessioned2015-09-15T18:15:59Z-
dc.date.available2015-09-15T18:15:59Z-
dc.date.issued2010
dc.identifier.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-77958004175&partnerID=40&md5=7507b929c5d028719c28656f385e6abf
dc.identifier.urihttp://hdl.handle.net/20.500.12104/42411-
dc.description.abstractBackground And Purpose-: Cerebellar venous infarction or hemorrhage due to isolated venous thrombosis of the posterior fossa is a rare form of intracranial vein thrombosis that can be unsuspected in clinical practice. Methods-: We studied 230 patients with intracranial vein thrombosis, identifying 9 (3.9%: 7 women, mean age 34 years) with neuroimaging or histopathologic evidence of localized posterior fossa vein thrombosis causing parenchymal injury limited exclusively to the cerebellum. Results-: All patients had an insidious presentation suggesting other diagnoses. Intracranial hypertension (n=6) and cerebellar (n=4) syndromes were the main clinical presentations. Intracranial vein thrombosis was idiopathic in 3 patients; associated with puerperium in 3; and with contraceptives, protein C deficiency, and dehydration in 1 case each. CT was abnormal but not diagnostic in 5 patients, showing a cerebellar hypodensity with fourth ventricle compression and variable hydrocephalus in 5 patients, and cerebellar hemorrhage in 2. Conventional MRI provided diagnosis in 6 cases, showing the causal thrombosis and cerebellar involvement; angiography was practiced in 2 of them, confirming the findings identified by MRI. In the other 3 patients, diagnosis was reached by histopathology. Thromboses were localized at the straight sinus (n=4), lateral sinuses (n=3), and superior petrosal vein (n=2). The acute case fatality rate was 22.2% (n=2), 1 (11.1%) patient was discharged in a vegetative state, 1 (11.1%) was severely disabled, and 5 (55.6%) were moderately disabled. Conclusions-: Isolated venous thrombosis of the posterior fossa is infrequent and implies a challenging diagnosis. Risk factors for intracranial vein thrombosis and atypical cerebellar findings on CT should lead to further MRI assessment. � 2010 American Heart Association, Inc.
dc.relation.isreferencedbyScopus
dc.relation.isreferencedbyWOS
dc.titleIsolated vein thrombosis of the posterior fossa presenting as localized cerebellar venous infarctions or hemorrhages
dc.typeArticle
dc.identifier.doi10.1161/STROKEAHA.110.588202
dc.relation.ispartofjournalStroke
dc.relation.ispartofvolume41
dc.relation.ispartofissue10
dc.relation.ispartofpage2358
dc.relation.ispartofpage2361
dc.subject.keywordcerebellum; cerebral vein thrombosis; posterior fossa; sinus thrombosis; thrombosis
dc.contributor.affiliationRuiz-Sandoval, J.L., Department of Neurology and Neurosurgery, Hospital Civil de Guadalajara Fray Antonio Alcalde, Mexico, Department of Neurosciences, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara, Mexico; Chiquete, E., Department of Internal Medicine, Hospital Civil de Guadalajara Fray Antonio Alcalde, Universidad de Guadalajara, Guadalajara, Mexico; Navarro-Bonnet, J., Department of Neurology and Neurosurgery, Hospital Civil de Guadalajara Fray Antonio Alcalde, Mexico, Department of Neurosciences, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara, Mexico; Ochoa-Guzm�n, A., Department of Neurology and Neurosurgery, Hospital Civil de Guadalajara Fray Antonio Alcalde, Mexico, Department of Neurosciences, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara, Mexico; Arauz-G�ngora, A., Stroke Clinic, Instituto Nacional de Neurolog�a y Neurocirug�a, Mexico City, Mexico; Barinagarrementer�a, F., Stroke Clinic, Instituto Nacional de Neurolog�a y Neurocirug�a, Mexico City, Mexico; Cant�, C., Stroke Clinic, Instituto Nacional de Neurolog�a y Neurocirug�a, Mexico City, Mexico
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