Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/41875
Title: Hepatic artery reconstruction with inferior mesenteric vein graft in pediatric living donor liver transplantation
Author: Vivas-Arceo, C.
Benavides, S.A.
De Jesus Trujillo, J.
Panduro-Cerda, Arturo
Rivas-Estilla, A.M.
Issue Date: 2003
Abstract: In Latin America few studies have explored frequency and risk factors predicting hepatitis C virus (HCV) infection in blood donors. In this study we determined the prevalence of HCV infection in blood donors from West Mexico. Potential risk factors, clinical, histological and virologic characteristics presented in this group were also evaluated. Methods: HCV antibodies were evaluated in 57 108 blood donors with commercial second-generation enzyme immunoassays. Positive results were confirmed by a recombinant immunoblot assay. Repeatedly seropositive donors were further studied for risk factors, history for hepatitis, hepatic enzymes (aspartate aminotransferase and alanine aminotransferase (AST and ALT)), liver histology and hepatitis C virus-ribonucleic acid (HCV-RNA) detection. Results: A total of 499 blood donors were initially tested positive doubtful for antibodies to HCV Ab (0.8%). While there was no difference in HCV prevalence with respect to age or gender, the most frequent risk factors identified were transfusion (42%), household exposure (14.8%), multiple sex partner (6.8%) and intranasal cocaine use (2.3%). Also, we found that from a subgroup of donors tested for histological analysis, 19% presented abnormal ALT levels and 90% showed abnormal liver histology. No correlation was found between abnormal ALT levels and the presence of HCV-RNA in serum. Conclusion: These results demonstrate a low prevalence (0.8%) of HCV infection among Western Mexican blood donors, which was comparable to those established for Western countries, but in contrast in our study the most frequent risk factor continues being transfusion followed by household exposure. " 2002 Elsevier Science B.V. All rights reserved.",,,,,,"10.1016/S1386-6346(02)00243-7",,,"http://hdl.handle.net/20.500.12104/41875","WOS",,,,,,"2",,"Hepatology Research",,"115
123",,"25",,"Scopus",,,,,,"Alanine aminotransferase; Aspartate aminotransferase; Blood donors; Hepatitis C virus; Hepatitis C virus ribonucleic acid; Reverse transcription-polymerase chain reaction",,,,,,"Hepatitis C virus: Prevalence and routes of infection among blood donors of West Mexico",,"Article" "43675","123456789/35008","Vazquez-Valls, E., Unidad de Investigación Médica en Epidemiología Clínica, UMAE, Hospital de Especialidades, CMNO, IMSS, Mexico; Flores-Soto, M.E., Lab. de Neurobiología Celular y Molecular, División de Neurociencias, CIBO, IMSS, Mexico; Chaparro-Huerta, V., Lab. de Neurobiología Celular y Molecular, División de Neurociencias, CIBO, IMSS, Mexico; Torres-Mendoza, B.M., Lab. de Neurobiología Celular y Molecular, División de Neurociencias, CIBO, IMSS, Mexico, Instituto de Patología Infecciosa y Experimental, CUCS, U. de G., Mexico; Gudiño-Cabrera, G., Lab. de Regeneración y Desarrollo Neural, Instituto de Neurobiología, Departamento de Biología Celular y Molecular, CUCBA, Mexico; Rivera-Cervantes, M.C., Lab. de Neurobiología Celular y Molecular, CUCBA, U. DE G., Mexico; Pallas, M., Unitat de Farmacologia i Farmacognòsia i Institut de Biomedicina (IBUB), CIBERNED, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain; Camins, A., Unitat de Farmacologia i Farmacognòsia i Institut de Biomedicina (IBUB), CIBERNED, Facultat de Farmàcia, Universitat de Barcelona, 08028 Barcelona, Spain; Armendáriz-Borunda, J., Inst. de Biología Molecular y Terapia Génica, CUCS, U. de G., Guadalajara Jalisco, Mexico; Beas-Zarate, C., Lab. de Neurobiología Celular y Molecular, División de Neurociencias, CIBO, IMSS, Mexico, Lab. de Regeneración y Desarrollo Neural, Instituto de Neurobiología, Departamento de Biología Celular y Molecular, CUCBA, Mexico
Beas-Zárate, Carlos., Universidad de Guadalajara. Centro Universitario de Ciencias Biológicas y Agropecuarias",,"Vazquez-Valls, E.
Flores-Soto, M.E.
Chaparro-Huerta, V.
Torres-Mendoza, B.M.
Gudino-Cabrera, G.
Rivera-Cervantes, M.C.
Pallas, M.
Camins, A.
Armendariz-Borunda, J.
Beas-Zárate, Carlos",,"2011",,"Hypoxia-inducible factor-1 alpha (HIF-1?) is a master transcription factor that regulates the response to hypoxia and ischemia and induces the expression of various genes, including vascular endothelial growth factor (VEGF) and erythropoietin (EPO). This study shows the systemic response of increased HIF-1?, EPO, and VEGF mRNA and protein. In addition, VEGF expression was increased in neurons and over-expressed in glial cells in a model of neuroexcitotoxicity in the hippocampus, in which rats were neonatally exposed to high glutamate concentrations. Simultaneous increases in HIF-1?, EPO and VEGF mRNA in peritoneal macrophages were also observed. Our study is consistent with the hypothesis that these genes exert a protective effect in response to neurotoxicity. © 2011 Elsevier B.V.",,,,,,"10.1016/j.jneuroim.2011.06.001",,,,"http://www.scopus.com/inward/record.url?eid=2-s2.0-80052829111&partnerID=40&md5=2bff33996f83add47b50c985b731cfa4
http://hdl.handle.net/20.500.12104/41896",,,,,,"01-feb",,"Journal of Neuroimmunology",,"12
18",,"238",,"Scopus
WOS",,,,,,"EPO; Excitotoxicity; HIF-1 alpha; Hippocampus; Macrophages; VEGF",,,,"HIF-1? expression in the hippocampus and peripheral macrophages after glutamate-induced excitotoxicity",,,,"Article", "43647","123456789/35008",,"Margreiter, C., Department of General and Transplant Surgery, Innsbruck Medical University, Austria; Aigner, F., Department of General and Transplant Surgery, Innsbruck Medical University, Austria; Orozco, H., General Surgery Department, Hospital Civil de Guadalajara, Universidad de Guadalajara, Jalisco, Mexico; Wechselberger, G., Department of Plastic and Reconstructive Surgery, Innsbruck Medical University, Austria; Ollinger, R., Department of General and Transplant Surgery, Innsbruck Medical University, Austria; B sm ller, C., Department of General and Transplant Surgery, Innsbruck Medical University, Austria; Sucher, R., Department of General and Transplant Surgery, Innsbruck Medical University, Austria; Mark, W., Department of General and Transplant Surgery, Innsbruck Medical University, Austria; Margreiter, R., Department of General and Transplant Surgery, Innsbruck Medical University, Anichstrasse 35, Innsbruck A-6020, Austria, Department of General and Transplant Surgery, Innsbruck Medical University, Austria",,"Margreiter, C.
Aigner, F.
Orozco, H.
Wechselberger, G.
Ollinger, R.
Bosmuller, C.
Sucher, R.
Mark, W.
Margreiter, R.",,"2008",,"We report a transplant of the left lateral liver segments with two arteries for a pediatric recipient from a live donor. A six-month-old female patient was diagnosed with liver cirrhosis secondary to biliary atresia and scheduled for LDLT (father as donor). Left lateral hepatectomy was performed at the donor site. The dissection of the left HA, which divided immediately after its origin, showed two branches for segments II and III. The artery for segment III was anastomosed to the recipient HA. The artery for segment II was too short for direct anastomosis with the gastroduodenal artery. After an unsuccessful attempt to use of the recipient's saphenous vein, the recipient's IMV was used as an interposition graft. No post-operative complications were observed. The outcome of this case demonstrates that left lateral segments with two arteries can be successfully used if proper surgical techniques are applied. From this experience we can recommend the IMV as an alternative to the saphenous vein for an interposition graft. Copyright " 2008 Blackwell Munksgaard.
URI: http://hdl.handle.net/20.500.12104/41868
http://www.scopus.com/inward/record.url?eid=2-s2.0-42949112995&partnerID=40&md5=43eb262989e513020225603a17749723
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