Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/41434
Title: Factors associated with hyperhomocysteinaemia in Mexican patients with rheumatoid arthritis
Author: Alam, M.M.
Miras, J.
Perez-Carrillo, L.A.
Vilchez, S.
Solans, C.
Imae, T.
Ujihara, M.
Esquena, J.
Issue Date: 2013
Abstract: A simple method to synthesize carbonaceous porous foams is described, forming simultaneously micropores and macropores, by polymerizing in the external phase of highly concentrated water-in-oil (W/O) emulsions, and pyrolizing the resulting macroporous polymer foam. Highly concentrated W/O emulsions were prepared with 1,1-dichloroethene monomer in the external phase, which was polymerized at low temperature by a redox initiator. Monolithic low-density macroporous foams were obtained after polymerization and purification by soxhlet extraction. These foams were mainly macroporous, with low surface area (?28 m2 g-1) and negligible microporosity and mesoporosity, as expected. The size (2-10 ?m) and morphology of the macropores were consistent with the droplet size (2-10 ?m) and shape (polyhedral) of the highly concentrated W/O emulsions. Pyrolization of the macroporous polymer foams allowed the formation of micropores while the macroporous texture was preserved, and consequently, dual micro/macroporous carbonaceous monoliths were obtained, with a large surface area (>800 m 2 g-1). These materials were characterized by optical microscopy, scanning and transmission electron microscopy, N2 sorption isotherms, infrared absorption spectroscopy and elemental analysis. The influence of pyrolysis temperature (300, 400 and 500 C) was studied. " 2013 Elsevier Inc. All rights reserved.",,,,,,"10.1016/j.micromeso.2013.08.015",,,"http://hdl.handle.net/20.500.12104/41434","http://www.scopus.com/inward/record.url?eid=2-s2.0-84884166753&partnerID=40&md5=157e4e79c375d2bd13329534d3c4ae31",,,,,,,,"Microporous and Mesoporous Materials",,"102
108",,"182",,"Scopus
WOS",,,,,,"Carbonaceous foams; Highly concentrated emulsions; Micro/macro dual porous materials",,,,,,"Facile synthesis of dual micro/macroporous carbonaceous foams by templating in highly concentrated water-in-oil emulsions",,"Article" "43226","123456789/35008",,"Vázquez-Cárdenas, A., División de Genética, Instituto Mexicano del Seguro Social, Universidad de Guadalajara, Guadalajara, Jal., Mexico; Vásquez-Velásquez, A.I., División de Genética, Instituto Mexicano del Seguro Social, Universidad de Guadalajara, Guadalajara, Jal., Mexico; Barros-Núñez, P., División de Genética, Instituto Mexicano del Seguro Social, Universidad de Guadalajara, Guadalajara, Jal., Mexico; Mantilla-Capacho, J., División de Genética, Instituto Mexicano del Seguro Social, Universidad de Guadalajara, Guadalajara, Jal., Mexico; Rocchi, M., Dipartimento di Genetica e Microbiologia, University di Bari, Bari, Italy; Rivera, H., División de Genética, Instituto Mexicano del Seguro Social, Universidad de Guadalajara, Guadalajara, Jal., Mexico, División de Genética, Instituto Mexicano del Seguro Social, Ap. Postal 1-3838, Guadalajara, Jal., Mexico",,"Vazquez-Cardenas, A.
Vasquez-Velasquez, A.I.
Barros-Nunez, P.
Mantilla-Capacho, J.
Rocchi, M.
Rivera, H.",,"2007",,"We report here on 3 familial whole-arm translocations (WATs), namely the 8th instance of t(1;19)(p10;q10) and 2 novel exchanges: t(9;13)(p10;q10) and t(12;21)(p10;q10). The exchanges (1;19) and (12;21) were ascertained through a balanced carrier, whereas the t(9;13) was first diagnosed in a boy with a trisomy 9p syndrome and der(9p13p). Results of FISH analyses with the appropriate ?-satellite probes were as follows. Family 1, t(1;19): the D1Z5 probe gave a strong signal on both the normal chromosome 1 and the der(1q19p) as well as a weak signal on the der(1p19q). Family 2, t(9;13): the centromere-9 alphoid and D13Z1/D21Z1 probes under standard stringency gave no signal on the der(9p13p) in both the proband and a carrier brother, whereas the der(9q13q) was labelled only with the centromere-9 alphoid repeat in the latter; yet, this probe under low stringency revealed a residual amount of alphoid DNA on the der(9p13p) in the carrier. Family 3, t(12;21): the D12Z3 probe gave a signal on the normal chromosome 12 and the der(12p21q), whereas the D13Z1/D21Z1 repeat labelled the der(12q21p), the normal chromosome 21, and both chromosomes 13. Out of 101 WATs compiled here, 73 are distinct exchanges, including 32 instances between chromosomes with common alphoid repeats. Moreover, 7/9 of recurrent WATs involved chromosomes from the same alphoid family. Thus constitutional WATs appear to recur more frequently than other reciprocal exchanges, often involve chromosomes with common alphoid repeats, and can mostly be accounted for the great homology in alphoid DNA that favours mispairing and illegitimate nonhomologous recombination.",,,,,,,,,"http://hdl.handle.net/20.500.12104/41447","http://www.scopus.com/inward/record.url?eid=2-s2.0-34548269996&partnerID=40&md5=c307c0d74a5c7a0bce3a4e1d150abad6
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=17666779",,,,,,"3",,"Journal of Applied Genetics",,"261
268",,"48",,"Scopus
MEDLINE
WOS",,,,"Index Medicus;Abnormalities, Multiple/ge [Genetics];Abnormalities, Multiple/pa [Pathology];Adolescent;Centromere;Child;Chromosomes, Human, Pair 1/ge [Genetics];Chromosomes, Human, Pair 12/ge [Genetics];Chromosomes, Human, Pair 13/ge [Genetics];Chromosomes, Human, Pair 19/ge [Genetics];Chromosomes, Human, Pair 21/ge [Genetics];Chromosomes, Human, Pair 9/ge [Genetics];Craniosynostoses/ge [Genetics];Craniosynostoses/pa [Pathology];Family;Female;Humans;In Situ Hybridization, Fluorescence;Karyotyping;Male;Phenotype;Recombination, Genetic;Repetitive Sequences, Nucleic Acid;Translocation, Genetic;Trisomy",,"Alphoid DNA; Human chromosomes; translocation (1;19); Translocation (12;21); Translocation (9;13); Whole-arm exchange",,,,,,"Familial whole-arm translocations (1;19), (9;13), and (12;21): A review of 101 constitutional exchanges",,"Article" "43256","123456789/35008",,"Raymundo-Huizar, A.R., Universidad de Guadalajara Centro Universitario de la Costa, Departamento de Ciencias Médicas y Biológicas, Av. Universidad 203, Puerto Vallarta 48280 Jalisco, Mexico; Lozano, M.S., Universidad de Guadalajara Centro Universitario de la Costa Sur, Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Gómez Farias 82, San Patricio-Melaque 48280 Jalisco, Mexico",,"Raymundo-Huizar, A.R.
Lozano, M.S.",,"2008",,"The stomach content of the common searobin Prionotus ruscarius is described and analysed in this study. A total of 128 specimens, were captured from the continental shelf of Jalisco and Colima, Mexico, between January and December 1996. Percentages of numeric, gravimetric, frequency of occurrence and index of relative importance (IIR) were calculated for each prey item. Thirty food items were observed in the diet. The index of relative importance (IIR) showed that P. ruscarius mainly prey on penaeids shrimp (45.5%), brachyuran (37.8%) and stomatopods (9.7%). Significant feeding variations were found in different fish body sizes. According to Levins Index, used to determine the trophic spectrum, P. ruscarius had a medium grade of specialization. Penaeid shrimps and brachyurans were observed as secondary food items, based on the feeding index.",,,,,,,,,"http://hdl.handle.net/20.500.12104/41477","http://www.scopus.com/inward/record.url?eid=2-s2.0-51549107746&partnerID=40&md5=fb7bf980bd6fd26ecf91dc408f811246",,,,,,"1",,"Revista de Biologia Marina y Oceanografia",,"7
15",,"43",,"Scopus
WOS",,,,,,"Continental shelf; Stomach content; Triglidae",,,,,,"Feeding habits of the triglid fish Prionotus ruscarius (Gilbert and Starks, 1904) during 1996, on the Jalisco and Colima coast, México [Hábitos alimentarios del pez triglido Prionotus ruscarius (Gilbert and Starks, 1904) durante 1996, en las coastas de Jalisco y Colima, México]",,"Article" "43220","123456789/35008",,"Lopez-Olivo, M.A., Department of Internal Medicine - Rheumatology, Hospital General Regional 110, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Mexico; Gonzalez-Lopez, L., Department of Internal Medicine - Rheumatology, Hospital General Regional 110, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Mexico, Salto del Agua 2192, Col. Jardines del Country, Guadalajara, Jalisco, CP 44210, Mexico; García-Gonzalez, A., Baylor College of Medicine, Houston, TX, United States; Villa-Manzano, A.I., Department of Internal Medicine - Rheumatology, Hospital General Regional 110, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Mexico; Cota-Sanchez, A.R., Department of Blood Chemistry, Central Laboratory, Centro Médico Nacional de Occidente, Guadalajara, Mexico; Salazar-Paramo, M., Section of Studies for Musculoskeletal and Autoimmune Diseases, Clinical Epidemiology Research Unit, Hospital de Especialidades, Guadalajara, Mexico; Varon-Villalpando, E., Department of Clinical Pathology, Hospital General Regional 110, IMSS, Guadalajara, Mexico; Cardona-Muñoz, E.G., Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico; Gamez-Nava, J., Section of Studies for Musculoskeletal and Autoimmune Diseases, Clinical Epidemiology Research Unit, Hospital de Especialidades, Guadalajara, Mexico",,"Lopez-Olivo, M.A.
Gonzalez-Lopez, L.
García-Gonzalez, A.
Villa-Manzano, A.I.
Cota-Sanchez, A.R.
Salazar-Paramo, M.
Varon-Villalpando, E.
Cardona-Munoz, E.G.
Gamez-Nava, J.",,"2006",,"Background: Hyperhomocysteinaemia is a factor related to the development of atherosclerosis in rheumatoid arthritis (RA). However, Hispanics with RA develop high rates of coronary disease; there are no studies about the frequency and factors related to high levels of homocysteine in Mexican patients. Objective: To evaluate the prevalence and characteristics associated with hyperhomocysteinaemia in Mexican patients with RA. Methods: One hundred and fifty-two patients with RA were compared with 153 controls. The assessment in RA included clinical characteristics, disease activity (RADAR), functioning (HAQ-Di and global functional status), comorbidity, and radiological damage. Laboratory determinations included total serum homocysteine (tHcy), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF), and lipid profile. Results: Median levels of homocysteine were higher in RA compared with controls (11.3 vs. 9.3, p < 0.001). Twenty per cent of the patients with RA had hyperhomocysteinaemia (> 15 ?mol/L) compared with 6% in controls (p < 0.001). There was statistical association between hyperhomocysteinaemia in RA with male gender (p < 0.001), impairment in the global functional status (p=0.004), higher radiological damage (p=0.001), and CRP (p=0.04). There was no association with RADAR, HAQ-Di, or RF, methotrexate dose or duration of use. In the adjusted multivariate model, the two variables associated with higher risk for hyperhomocysteinaemia were male gender (OR=4.2, 95% CI 2 to 12, p=0.006) and higher radiological damage (III-IV) (OR=3.4, 95% CI 1.3 to 9, p=0.01). Conclusions: Our data show a high prevalence of hyperhomocysteinaemia in Mexican patients with RA. More effort is required to evaluate and treat earlier this coronary risk factor. " 2006 Taylor & Francis on license from Scandinavian Rheumatology Research Foundation.
URI: http://hdl.handle.net/20.500.12104/41441
http://www.scopus.com/inward/record.url?eid=2-s2.0-33646487450&partnerID=40&md5=97e950a81d487c59026d5c0abe7cffb3
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