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|Title:||Epidemiological risk for Trypanosoma cruzi transmission by species of Phyllosoma complex in the occidental part of Mexico|
De La Mora, P.G.
|Abstract:||Cardiovascular diseases and type 2 diabetes are the major causes of mortality in Mexico. Metabolic syndrome (MS) is a cluster of factors that increase the risk to develop such diseases. Previous studies have shown that MS is associated with high tumor necrosis factor (TNF-?) levels. In fact, TNF-? has been proposed to be a useful marker for clinical diagnosis of inflammation at an early stage. Therefore, we analyzed TNF-? concentrations in Mexican individuals with or without MS and related these levels to the associated MS components. Clinical, anthropometric, and biochemical data were analyzed in 41 healthy and 39 MS individuals. Individuals were similarly grouped by age and gender. The serum TNF-? levels measured by a highly sensitive enzyme-linked immunosorbent assay (ELISA) kit were increased significantly in MS subjects compared with healthy individuals (P<0.001). The assay showed 78.1% sensitivity and 61.5% specificity with a cut-point level of 1.36pg/mL. TNF-? levels higher than the cut-point value were correlated with insulin resistance indices. These findings support the hypothesis that serum TNF-? concentration could be a useful marker for early MS diagnosis. Nevertheless, we suggest the establishment of specific cut-point values in each studied population to evaluate potential clinical applications. " 2009 Wiley-Liss, Inc.",,,,,,"10.1002/jcla.20289",,,"http://hdl.handle.net/20.500.12104/41295","http://www.scopus.com/inward/record.url?eid=2-s2.0-58849120141&partnerID=40&md5=9e9208d8341ce5133a800ee3891c420e|
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=19140212",,,,,,"1",,"Journal of Clinical Laboratory Analysis",,"51
WOS",,,,"Index Medicus;Adult;Aged;Anthropometry;Biological Markers/bl [Blood];Blood Chemical Analysis;Blood Pressure;Chi-Square Distribution;Enzyme-Linked Immunosorbent Assay;Female;Humans;Male;Metabolic Syndrome X/di [Diagnosis];Metabolic Syndrome X/ep [Epidemiology];Mexico;Middle Aged;ROC Curve;Reference Values;Sensitivity and Specificity;Tumor Necrosis Factor-alpha/bl [Blood]",,"Cytokine; Diagnosis; Insulin resistance; Marker; TNF-?",,,,,,"Establishment of a cut-point value of serum TNF-? levels in the metabolic syndrome",,"Article" "43042","123456789/35008",,"Magallán-Gastélum, E., Departamento de Salud Pública, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Apartado postal 4-119, Guadalajara, Jalisco, Mexico; Lozano-Kasten, F., Departamento de Salud Pública, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Apartado postal 4-119, Guadalajara, Jalisco, Mexico; Gutiérrez, M.S., Departamento de Salud Pública, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Apartado postal 4-119, Guadalajara, Jalisco, Mexico; Flores-Pérez, A., Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, AP 70228, CP 04510, México D.F., Mexico; Sánchez, B., Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, AP 70228, CP 04510, México D.F., Mexico; Espinoza, B., Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, AP 70228, CP 04510, México D.F., Mexico; Bosseno, M.-F., Institut de Recherche Pour Le Developpement (IRD), UR 008 Pathologenie et Epidemiologie des Trypanosomatides, BP 64501, CP 34394, Montpellier, France; Breni-re, S.F., Institut de Recherche Pour Le Developpement (IRD), UR 008 Pathologenie et Epidemiologie des Trypanosomatides, BP 64501, CP 34394, Montpellier, France",,"Magallon-Gastelum, E.
Breniere, S.F.",,"2006",,"Domestic and peridomestic triatomine populations were collected in three rural Mexican communities of Jalisco, Nayarit and Zacatecas states. Triatoma longipennis and T. picturata (Phyllosoma complex) were the principal species unequally distributed in the villages: T. longipennis was the main species in two communities and T. picturata in the third one. Peridomestic infestation and colonization indexes were remarkably high ranging from 26.1% to 50% and from 58.3% to 85.7%, respectively. Moreover, domestic (indoor) infestation was observed in only one of the communities infested by T. longipennis. The preliminary study of temporal variation indicates increasing trend of the triatomine population and infestation rates during the dry season. Triatomine infection rates ranged from 41.2% to 60.2% and all the flagellate isolates were assigned to T. cruzi I. The majority of the dwellings were built with modern building materials and the sanitary conditions were generally good. High peridomestic infestations must be considered as a risk factor of Chagas disease transmission and further studies are needed to better understand the peridomestic conditions favoring the establishment of the triatomines. The contribution of such study to enlarger knowledge of epidemiological features of Chagas disease in Mexico is considered. " 2006 Elsevier B.V. All rights reserved.
|Appears in Collections:||Producción científica UdeG|
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