Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/41077
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dc.contributor.authorGomez-Meda, B.C.
dc.contributor.authorBarros-Hernandez, A.
dc.contributor.authorGuzman-Barcenas, J.
dc.contributor.authorLemus-Varela, M.D.L.
dc.contributor.authorZamora-Perez, A.L.
dc.contributor.authorTorres-Mendoza, B.M.
dc.contributor.authorGallegos-Arreola, M.P.
dc.contributor.authorArmendariz-Borunda, J.
dc.contributor.authorZuniga-Gonzalez, G.M.
dc.date.accessioned2015-09-15T17:50:21Z-
dc.date.available2015-09-15T17:50:21Z-
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/20.500.12104/41077-
dc.identifier.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-84910674684&partnerID=40&md5=f9e5b7baedea80ed49f6c235f2585af3
dc.identifier.urihttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25463679
dc.description.abstractIn previous studies, exposure to phototherapy, but not oxygen therapy, resulted in damage to genetic material in newborns. The objective of this study was to determine whether micronucleated erythrocytes (MNE) increased in preterm newborns (PNBs) who were exposed to blue light phototherapy lamps. MNE of mature organisms are rapidly eliminated by the spleen, and the presence of MNE has been related to immaturity in some species. Furthermore, PNBs present spontaneous MNE. Blood samples were taken from 17 PNBs at birth to establish baseline frequencies (0 h). After beginning blue light phototherapy, blood samples were obtained from 11 of these PNBs at 24-h intervals for 96 h, after the baseline sample. MNE and micronucleated polychromatic erythrocytes (MNPCE) were counted. The basal values of MNE and MNPCE from 17 PNBs were 0.62 0.48 and 1.52 1.28 (), respectively, and no increase in MNE or MNPCE was observed in the serial samples of 11 PNBs exposed to blue light and oxygen therapies, though previous studies reported increases using other types of lamps. In conclusion, under the conditions described no increase in the number of MNE or MNPCE was observed in the peripheral blood of PNBs exposed to blue light phototherapy. 2014 Elsevier B.V. All rights reserved.
dc.relation.isreferencedbyScopus
dc.relation.isreferencedbyWOS
dc.relation.isreferencedbyMEDLINE
dc.titleEffects of blue light phototherapy on DNA integrity in preterm newborns
dc.typeArticle
dc.identifier.doi10.1016/j.jphotobiol.2014.09.012
dc.relation.ispartofjournalJournal of Photochemistry and Photobiology B: Biology
dc.relation.ispartofvolume141
dc.relation.ispartofpage283
dc.relation.ispartofpage287
dc.subject.keywordIndex Medicus
dc.contributor.affiliationGómez-Meda, B.C., Instituto de Biología Molecular en Medicina, Departamento de Biología Molecular y Genómica, Universidad de GuadalajaraGuadalajara, Jalisco, Mexico; Barros-Hernández, A., Laboratorio de Mutagénesis, Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro SocialGuadalajara, Jalisco, Mexico, Servicio de Neonatología Del Hospital Infantil de México Federico GómezDistrito Federal, Mexico; Guzmán-Bárcenas, J., Servicio de Neonatología Del Hospital Infantil de México Federico GómezDistrito Federal, Mexico; Lemus-Varela, M.D.L., Departamento de Neonatología, Hospital de Pediatría, Instituto Mexicano Del Seguro SocialGuadalajara, Jalisco, Mexico; Zamora-Perez, A.L., Instituto de Investigación en Odontología, Departamento de Clínicas Odontológicas Integrales, Universidad de GuadalajaraGuadalajara, Jalisco, Mexico; Torres-Mendoza, B.M., División de Neurociencias, Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro SocialGuadalajara, Jalisco, Mexico, Departamento de Clínicas Médicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, GuadalajaraJalisco, Mexico; Gallegos-Arreola, M.P., Laboratorio de Genética Molecular, Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro SocialGuadalajara, Jalisco, Mexico; Armendáriz-Borunda, J., Instituto de Biología Molecular en Medicina, Departamento de Biología Molecular y Genómica, Universidad de GuadalajaraGuadalajara, Jalisco, Mexico; Zúñiga-González, G.M., Laboratorio de Mutagénesis, Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro SocialGuadalajara, Jalisco, Mexico
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