Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/40997
Title: Effect of renutrition on natural and cell-mediated immune response in infants with severe malnutrition
Author: Vasquez-Garibay, E.
Campollo-Rivas, O.
Romero-Velarde, E.
Mendez-Estrada, C.
Garcia-Iglesias, T.
Alvizo-Mora, J.G.
Vizmanos-Lamotte, B.
Issue Date: 2002
Abstract: Background: The purpose of this study was to evaluate whether a 4-week nutritional recovery period with a starting infant formula and 3.35 kJ/mL energy density would favorably affect the natural and cell-mediated immune response in infants with severe and primary protein-energy malnutrition. Methodology: The study included 12 severely malnourished infants, 3 to 18 months of age. For 2 weeks, infants were fed a starting infant formula, with energy density increased to 0.8 kcal/mL, through a nasogastric tube. Infants were fed "ad libitum" for 2 more weeks. On the fifth day, 837 kJ/kg and 4 g/kg protein were given daily. At the beginning and at the end of the 4-week period, weight, length, phagocytosis, microbicidal activity, chemotaxis, and cell proliferation indices were measured. Null hypothesis was rejected with a paired t test and a P value less than 0.05. Results: After the 4-week period of nutritional recovery, the weight and length indicators and the four immunologic assays showed significant increase (P < 0.005). Conclusion: The study demonstrated that a 4-week nutritional recovery period with a starting infant formula and 0.8 kcal/mL energy density favorably affected the natural and cell-mediated immune response in infants with severe protein-energy malnutrition. � 2002 Lippincott Williams & Wilkins, Inc.
URI: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036239653&partnerID=40&md5=1b3d0b89d1630472584f3cd9380e296e
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med4&AN=11964957
http://hdl.handle.net/20.500.12104/40997
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