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|Title:||Effect of particle size on the swelling and compression modulus of nanostructured polyacrylamide hydrogels|
|Abstract:||The objective of the present study is to demonstrate the effect of nucleotide intake and intensive nutritional support on the concentration of insulin-like growth factor I (IGF-I) and other hormonal biomarkers in severely malnourished children. Twenty-six severely malnourished children <48 months of age received formula without lactose via enteral feeding for 2 weeks and ad libitum for an additional 2 weeks. Anthropometrical measurements were performed and serum concentrations of IGF-I, insulin-like growth factor binding protein-3 (IGFBP-3), leptin, soluble leptin receptor (sOB-R), as well as the estimated molar excess of sOB-R over leptin were obtained. Two groups were formed. One group received formula with nucleotides (NT+; n 13) and the other without nucleotides (NT-; n 13). A control group was included (n 13). Parametric and nonparametric tests as well as ANOVA models were used. Nutritional recovery, nucleotides intake, type of malnutrition, age and the interaction between gender and malnutrition influenced the concentration of IGF-I (P<0.001). Nutritional recovery, nucleotides intake, gender and type of malnutrition had an effect on IGFBP-3 (P<0.001). Nutritional recovery had a significant effect on serum leptin (P=0.001). Age and nutritional recovery had an effect on sOB-R (P<0.001); all variables included affected the molar excess of sOB-R over leptin (P<0.001). In conclusion, nucleotide intake and nutritional recovery had a notable effect on IGF-I, IGFBP-3 and other hormonal biomarkers. This outcome could stimulate the catch-up growth of severely malnourished infants and toddlers during the nutritional recovery period. " The Authors 2006.",,,,,,"10.1079/BJN20061879",,,"http://hdl.handle.net/20.500.12104/40975","http://www.scopus.com/inward/record.url?eid=2-s2.0-33947542386&partnerID=40&md5=43516c16ba34a51d3b713798dd6d3b43",,,,,,"4",,"British Journal of Nutrition",,"683|
WOS",,,,,,"Children; Insulin-like growth factor I; Leptin; Malnutrition; Nucleotides; Nutritional recovery",,,,,,"Effect of nucleotide intake and nutritional recovery on insulin-like growth factor I and other hormonal biomarkers in severely malnourished children",,"Article" "42755","123456789/35008",,"Fisberg, M., University São Marcos, São Paulo, SP, Brazil; Maulén-Radován, I.E., Instituto Nacional de Pediatria, México DF, Mexico; Tormo, R., Hosp. Materno-Infantil Vall d'Hebron, Barcelona, Spain; Tabernero Carrascoso, M., Hospital Universitario La Paz, Madrid, Spain; Pedrín Giner, C., Hospital Niño Jesús, Madrid, Spain; Arguelles Martin, F., Complejo Hosp. Virgen Macarena, Sevilla, Spain; Pavón Belinchón, P., Hospital General de Galicia, Santiago de Compostela, Spain; Martínez Costa, C., Hosp. Clúnico Universitario, Valencia, Spain; Pérez Pérez, M., Complejo Hosp. Virgen del Rocio, Sevilla, Spain; Gonzalez Caro, J., Complejo Hosp. Virgen del Rocio, Sevilla, Spain; Vasquez Garibay, E.M., University of Guadalajara, Guadalajara, Mexico; García Aranda, J.A., Hospital Infantil de México, México DF, Mexico; Alfonso P , I.M., Hospital Doña Estefania, Lisboa, Portugal; Da Silva Guerra, A.J.M., Universidade de Porto, Porto, Portugal; Villagómez Martínez, S., Instituto Nacional de Pediatria, México DF, Mexico; McCue, M., Abbott Laboratories, Abbott Park, IL, United States; Alarcón, P.A., Abbott Laboratories, Abbott Park, IL, United States; Comer, G.M., Abbott Laboratories, Abbott Park, IL, United States, Abbott Laboratories, Bldg. AP30-2, Dept. R4NH, 200 Abbott Park Rd, Abbott Park, IL 60064-6149, United States",,"Fisberg, M.
Tabernero Carrascoso, M.
Pedron Giner, C.
Arguelles Martin, F.
Pavon Belinchon, P.
Martinez Costa, C.
Perez Perez, M.
Gonzalez Caro, J.
Vasquez Garibay, E.M.
García Aranda, J.A.
Alfonso Po, I.M.
Da Silva Guerra, A.J.M.
Villagomez Martinez, S.
Comer, G.M.",,"2002",,"Our objective was to evaluate incidence, duration of illness, and anthropometrics in children who received a nutritional supplement with or without synbiotics. A double-blind, randomized study was done with 1-6 year old children who were between -1SD and -3SD from the median of weight-for-height. Children received a nutrition supplement with (N=310) or without (N=316) synbiotics. The number of sick days per month decreased over four months for both groups (p<0.001), being more pronounced in 1 to 2 year old children (p<0.001). The synbiotic group experienced fewer constipation days (p=0.02) and both feeding groups experienced improved anthropometric measures (p<0.001). Underweight children, receiving an average of 40 mL/kg/day of a nutritional supplement, experienced catch-up growth and fewer sick days. The synbiotic group experienced a significant reduction in constipation among all ages and significantly reduced sick days among 3 to 5 year old children.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40976","http://www.scopus.com/inward/record.url?eid=2-s2.0-0036459780&partnerID=40&md5=2d3804775ebffa3dd53443037b895f18",,,,,,"4",,"International Pediatrics",,"216
222",,"17",,"Scopus",,,,,,"Fructooligosaccharides; Functional foods; Probiotic bacteria",,,,,,"Effect of oral nutritional supplementation with or without synbiotics on sickness and catch-up growth in preschool children",,"Article" "42756","123456789/35008",,"Gómez-García, A., Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Mexico, Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad, Instituto Mexicano del Seguro Social, Mexico, Centro de Investigación Biomédica de Michoacán, Instituto Mexicano del Seguro Social, Mexico; Hernández-Salazar, E., Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad, Instituto Mexicano del Seguro Social, Mexico; González-Ortiz, M., Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad, Instituto Mexicano del Seguro Social, Mexico; Martínez-Abundis, E., Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad, Instituto Mexicano del Seguro Social, Mexico, M. Urales 1409, Col. Independencia, 44340. Guadalajara, Mexico",,"Gomez-García, A.
Martinez-Abundis, E.",,"2006",,"Background: Zinc is important for insulin synthesis, storage and secretion. When zinc concentration decrease, there is a concomitant reduction in insulin secretion and peripheral insulin sensitivity Aim: To assess the effects of zinc sulfate on insulin sensitivity, leptin and androgens in obese individuals. Material and methods: A randomized, double-blind, placebo-controlled clinical trial was performed in 14 obese volunteers between 21 and 30 years old, with body mass index (BMI) ? 27 kg/m2. During one month, seven subjects received 100 mg/day of zinc sulfate orally (ZnG) and the other seven received placebo, as control group (CG). At baseline and after the intervention, insulin sensitivity was measured using a euglycemic-hyperinsulinemic clamp technique. Blood glucose, serum lipids, zinc, androgens and leptin were also measured in a fasting blood sample. Results: After the intervention, a rise in zinc concentrations from 11.8 to 16.9 umol/L; p=0.001 and in leptin levels from 15.2 to 27.7 ng/mL; p=0.029, was observed in the ZnG. No changes were observed in the CG. There were no significant changes in insulin sensitivity and androgens after the intervention with zinc sulfate. Conclusions: Zinc increased the leptin concentrations in obese individuals, but did not modify insulin sensitivity and androgens.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40977","http://www.scopus.com/inward/record.url?eid=2-s2.0-33646481921&partnerID=40&md5=da9967600400a1ff18f712ca73b6f2a4",,,,,,"3",,"Revista Medica de Chile",,"279
284",,"134",,"Scopus",,,,,,"Hyperinsulinism; Insulin; Leptin",,,,,,"Effect of oral zinc administration on insulin sensitivity, leptin and androgens in obese males [Efecto de la administración oral de zinc sobre sensibilidad a la insulina y niveles síricos de leptina y andrógenos en hombres con obesidad]",,"Article" "42759","123456789/35008",,"Alvarado, A.G., Departamento de Ingeniería Química, Universidad de Guadalajara, Blvd. M. García Barragán #1451Guadalajara, Jal., Mexico; Arellano, M., Departamento de Ingeniería Química, Universidad de Guadalajara, Blvd. M. García Barragán #1451Guadalajara, Jal., Mexico; Rabelero, M., Departamento de Ingeniería Química, Universidad de Guadalajara, Blvd. M. García Barragán #1451Guadalajara, Jal., Mexico; Puig, J.E., Departamento de Ingeniería Química, Universidad de Guadalajara, Blvd. M. García Barragán #1451Guadalajara, Jal., Mexico; Sánchez-Díaz, J.C., Departamento de Ingeniería Química, Universidad de Guadalajara, Blvd. M. García Barragán #1451Guadalajara, Jal., Mexico",,"Alvarado, A.G.
Sanchez-Diaz, J.C.",,"2015",,"The effects of concentration and size of polyacrylamide (PAM) nanoparticles on the swelling behavior and compression modulus of nanostructured polyacrylamide hydrogels are examined here. These hydrogels are made by free radical polymerization in an aqueous solution of acrylamide and a crosslinking agent containing dispersed crosslinked PAM nanoparticles of different sizes, previously made by inverse emulsion or microemulsion polymerization. Faster swelling rate and larger equilibrium swelling are observed as particle content increases or the nanoparticle size diminishes. The compression modulus depends on the concentration and size of the disperse nanoparticles: it is larger for hydrogels containing smaller particles at similar concentrations, and it increases as the nanoparticle concentration augments. Moreover, the nanostructured hydrogels have larger compression modulus than those of the conventional ones having similar swelling. " 2015 Taylor & Francis Group, LLC.
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