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Title: Chromosomal abnormalities in patients with azoospermia in western Mexico
Author: Meza-Espinoza, J.P.
Davalos-Rodriguez, I.P.
Rivera-Ramirez, H.
Perez-Munoz, S.
Rivas-Solis, F.
Issue Date: 2006
Abstract: In order to assess the frequency of chromosomal abnormalities in azoospermic males from western Mexico, we carried out a retrospective study in 227 patients. Forty-three (18.9%) cases with an abnormal karyotype were found. The most frequent chromosomal anomaly was 47,XXY, which was identified in 35 subjects (15.4%). In six cases (2.6%), structural aberrations were detected: two Robertsonian translocations [(45,XY,t(13;22)(p11;p11) and (45,XY,t(13;15) (p11;p11)], a Y;autosome translocation [46,XY,der(15)t(Y;15)(q12;p11)], and three mosaics [mos45,X/46,X,idic(Y)(q11)]. In general, these findings are in accordance with those from other surveys and confirm that the XXY aneuploidy is the most frequent chromosomal abnormality in azoospermic individuals. 2006 Informa UK Ltd All rights reserved.
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