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Title: Chromosomal abnormalities in patients with azoospermia in western Mexico
Author: Meza-Espinoza, J.P.
Davalos-Rodriguez, I.P.
Rivera-Ramirez, H.
Perez-Munoz, S.
Rivas-Solis, F.
Issue Date: 2006
Abstract: ? In order to assess the frequency of chromosomal abnormalities in azoospermic males from western Mexico, we carried out a retrospective study in 227 patients. Forty-three (18.9%) cases with an abnormal karyotype were found. The most frequent chromosomal anomaly was 47,XXY, which was identified in 35 subjects (15.4%). In six cases (2.6%), structural aberrations were detected: two Robertsonian translocations [(45,XY,t(13;22)(p11;p11) and (45,XY,t(13;15) (p11;p11)], a Y;autosome translocation [46,XY,der(15)t(Y;15)(q12;p11)], and three mosaics [mos45,X/46,X,idic(Y)(q11)]. In general, these findings are in accordance with those from other surveys and confirm that the XXY aneuploidy is the most frequent chromosomal abnormality in azoospermic individuals. Copyright � Taylor & Francis Group, LLC.
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