Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/39867
Title: Bursera fagaroides, effect of an ethanolic extract on ornithine decarboxylase (ODC) activity in vitro and on the growth of Entamoeba histolytica
Author: Rosas-Arreguin, P.
Arteaga-Nieto, P.
Reynoso-Orozco, R.
Villagomez-Castro, J.C.
Sabanero-Lopez, M.
Puebla-Perez, A.M.
Calvo-Mendez, C.
Issue Date: 2008
Abstract: The effect of an ethanolic extract from the stem bark of Bursera fagaroides on ornithine decarboxylase (ODC) activity in vitro and on the growth of Entamoeba histolytica was evaluated. For this purpose, increasing concentrations of the extract, up to 8.0 mg/mL, were added to amoeba cultures or ODC reaction mixtures, which were incubated at 37 �C. Metronidazole and G418 were added as controls. After 1.5 and 72 h, the ODC activity in vitro and growth, respectively, were determined. Results revealed a strong inhibition of growth with IC50 values on the order of 0.05 mg/mL. ODC activity, on the other hand, was inhibited by 12% and 50% at concentrations of 4.0 and 8.0 mg/mL, respectively. � 2008.
URI: http://www.scopus.com/inward/record.url?eid=2-s2.0-44249108048&partnerID=40&md5=a7fc16a66b105b709b6004bf49db5a84
http://hdl.handle.net/20.500.12104/39867
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