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|Title:||Accurate computation of transient profiles along multiconductor transmission systems by means of the numerical laplace transform|
|Abstract:||It has been reported that salicylates (sodium salicylate and aspirin) inhibit the replication of flaviviruses, such as Japanese encephalitis virus and dengue virus. Therefore, we considered it important to test whether acetylsalicylic acid (ASA) had anti-hepatitis C virus (HCV) activity. To this end, we examined the effects of ASA on viral replication and protein expression, using an HCV subgenomic replicon cell culture system. We incubated Huh7 replicon cells with 2-8 mM ASA for different times and measured HCV-RNA and protein levels by northern blot, real-time polymerase chain reaction, and western analysis, respectively. We found that ASA had a suppressive effect on HCV-RNA and protein levels (nearly 58%). ASA-dependent inhibition of HCV expression was not mediated by the 5?-internal ribosome entry site or 3?-untranslated regions, as determined by transfection assays using bicistronic constructs containing these regulatory regions. However, we found that HCV-induced cyclooxygenase 2 (COX-2) messenger RNA and protein levels and activity and these effects were down-regulated by ASA, possibly by a nuclear factor kappa B-independent mechanism. We also observed that the ASA-dependent inhibition of viral replication was due in part to inhibition of COX-2 and activation of p38 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 (MEK1/2) mitogen-activated protein kinases (MAPKs). Inhibition of these kinases by SB203580 and U0126, respectively, and by short interfering RNA silencing of p38 and MEK1 MAPK prevented the antiviral effect of ASA. Taken together, our findings suggest that the anti-HCV effect of ASA in the Huh7 replicon cells is due to its inhibitory effect on COX-2 expression, which is mediated in part by the activation of MEK1/2/p38 MAPK. Conclusion: These findings suggest the possibility that ASA could be an excellent adjuvant in the treatment of chronic HCV infection. Copyright " 2008 by the American Association for the Study of Liver Diseases.",,,,,,"10.1002/hep.22215",,,"http://hdl.handle.net/20.500.12104/39191","http://www.scopus.com/inward/record.url?eid=2-s2.0-43949109962&partnerID=40&md5=bbca2b19b28c36dc310883afa5b4302a",,,,,,"5",,"Hepatology",,"1462|
WOS",,,,,,,,,,,,"Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways",,"Article" "40952","123456789/35008",,"Burgos, J.E., University of Guadalajara-CEIC, Francisco de Quevedo 180, Col. Arcos de Vallarta, Guadalajara, Jalisco 44130, Mexico",,"Burgos, J.E.",,"2007",,"The rationale, scientific necessity, and character of intentionality ascriptions (assertions that attribute beliefs, expectations, wishes and such to certain systems) remain unresolved issues in the philosophy of mind and psychology. Foxall's proposed resolution (2007), which he calls "Intentional Behaviorism" (IB), is that intentionality ascriptions should be tied to the experimental analysis of behavior, nervous systems, and evolutionary considerations. Foxall's tone of scientific pluralism and attention to academic philosophy and psychology are steps in the right direction. However, I remain skeptical about IB's adequacy as a philosophical underpinning of psychology. My skepticism stems from IB's a-ontological character (which ignores the nature of intentionality, a major issue in psychology), pragmatist inclination (which invites relativism), and adoption of the linguistic view of intentionality, where intensionality is the defining criterion of intentionality. The linguistic view forces us either to restrict intentionality to humans, a deal-breaker for animal cognition psychologists, of to talk of mental language, a dealbreaker for operant psychologists. Also, an emphasis on extensionality, which is about logical validity and not soundness, fails to capture the emphasis of scientific psychology on evidence as a rationality criterion. Finally, if BB presupposes or entails linguistic antinativism, it is unlikely to appeal to evolutionary psychologists. IB would thus be better off by abandoning the linguistic view of intentionality.",,,,,,,,,"http://hdl.handle.net/20.500.12104/39173","http://www.scopus.com/inward/record.url?eid=2-s2.0-49749107091&partnerID=40&md5=26632cc784899b1e86cfaf6998d4cfd4",,,,,,,,"Behavior and Philosophy",,"65
76",,"35",,"Scopus",,,,,,"Cognitive psychology; Cognitivism; Correspondence; Evolutionary psychology; Experimental analysis; Extensionality; Intensionality; Intentional behaviorism; Intentionality; Linguistic view; Operant psychology; Pragmatism; Radical behaviorism; Scientific pluralism",,,,,,"About aboutness: Thoughts on intentional behaviorism",,"Review" "40963","123456789/35008",,"Flores-Ortega, J.R., Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Universidad de Guadalajara, V. Gómez Farías 82, San Patricio-Melaque 48980, JAL, Mexico; Godínez-Domínguez, E., Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Universidad de Guadalajara, V. Gómez Farías 82, San Patricio-Melaque 48980, JAL, Mexico; González-Sansín, G., Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Universidad de Guadalajara, V. Gómez Farías 82, San Patricio-Melaque 48980, JAL, Mexico; Rojo-Vázquez, J.A., Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Universidad de Guadalajara, V. Gómez Farías 82, San Patricio-Melaque 48980, JAL, Mexico; López-Prado, A.C., Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Universidad de Guadalajara, V. Gómez Farías 82, San Patricio-Melaque 48980, JAL, Mexico; Morales-Jauregui, M.Y., Departamento de Estudios para el Desarrollo Sustentable de Zonas Costeras, Universidad de Guadalajara, V. Gómez Farías 82, San Patricio-Melaque 48980, JAL, Mexico",,"Flores-Ortega, J.R.
Morales-Jauregui, M.Y.",,"2013",,"We analyzed the spatial distribution patterns of the five most abundant flatfish species caught by shrimp trawl nets on the continental shelf of the Mexican central Pacific. Food diets and trophic interactions between of the flatfish species are described as well. Flatfishes are distributed between 20 and 60 m depth. Bothus leopardinus showed the greatest abundance during the cold season (January-May), the other species did not show significant differences between seasons (cold and warm). The diet of the flatfish species consist of crustaceans, fishes and cephalopods. B. leopardinus and Syacium ovale are consumers of crustaceans, such as crabs, shrimps and stomatopods. Cyclopsetta panamensis, C. querna and Monolene assaedae based their diet in fishes and cephalopods. The feeding strategy of the five species analyzed is considered to be generalist, consuming a high number of preys in both seasons. Between the flatfish species, low values of overlapping in the diets were observed in size class and periods of the year. The flatfish species consume the available food resources and could change the preys consumed, according to prey availability, to avoid intra and interspecific competition.",,,,,,"103856/vol41-issue3-fulltext-6",,,"http://hdl.handle.net/20.500.12104/39184","http://www.scopus.com/inward/record.url?eid=2-s2.0-84884744761&partnerID=40&md5=6c909b2908dd6743a02d4a841fab9aea",,,,,,"3",,"Latin American Journal of Aquatic Research",,"423
WOS",,,,,,"Abundance; Distribution; Flatfish; Mexican central Pacific; Trophic ecology",,,,,,"Abundance, distribution, feeding habits and trophic interactions in five flatfish species (Pleuronectiformes) in the Mexican central Pacific [Abundancia, distribución, hábitos alimentarios e interacciones tróficas de cinco especies de lenguados (Pleuronectiformes) en el Pacífico central mexicano]",,"Article" "40972","123456789/35008",,,,"Fernández,Jesús A.
Hafner,Mark S.",,"2012",,,,,,,,"10.1021/jf030728+",,"0022-2372","http://hdl.handle.net/20.500.12104/39193","http://dx.doi.org/10.1644/11-MAMM-A-224.1",,,,"American Society of Mammalogists",,"2",,"Journal of mammalogy",,"560
571",,"93",,"BioOne",,,,,,,,,,,,"Molecular systematics and biogeography of the Mexican endemic kangaroo rat, Dipodomys phillipsii (Rodentia: Heteromyidae)",,"Journal Article" "40969","123456789/35008",,"Nuricumbo-Guillen, R., Electrical Engineering Department, SEPI-ESIME Zacatenco, Instituto Politécnico Nacional (IPN)Mexico City, Mexico; Gomez, P., Electrical Engineering Department, SEPI-ESIME Zacatenco, Instituto Politécnico Nacional (IPN)Mexico City, Mexico; Espino-Cortes, F.P., Electrical Engineering Department, SEPI-ESIME Zacatenco, Instituto Politécnico Nacional (IPN)Mexico City, Mexico; Uribe, F.A., Department of Mechanical and Electrical Engineering, Graduate Program on Electrical Engineering, Universidad de GuadalajaraGuadalajara, Mexico",,"Nuricumbo-Guillen, R.
Uribe, F.A.",,"2014",,"In this paper, transient internal profiles along multiconductor transmission lines are obtained from a model described in the q-s domain (spatial frequencyoral frequency). In such domain, the telegrapher equations of the line are defined in a direct algebraic form. Applying boundary conditions, these equations can be easily solved for V (q,s) and I (q,s). Then, the inverse numerical Laplace transform is applied successively (twice) to obtain v (z,t) and i (z,t), that is, the voltage and current profiles along the line. Besides, since the line's electrical parameters are defined in the frequency domain, the frequency dependence of such parameters is included in a straightforward manner. Test cases corresponding to an overhead line, a transformer winding, an underground power cable, and a transmission network are evaluated in order to demonstrate the accuracy and versatility of the proposed method. The results are compared with those obtained with Alternative Transients Program/Electromagnetic Transients Program and PSCAD/EMTDC at specific points along the transmission systems under analysis, given that the space discretization is cumbersome and prone to error accumulation in these time-domain simulation programs. " 2014 IEEE.
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