Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/39168
Title: Molecular epidemiology of HIV type 1 in Mexico: Emergence of BG and BF intersubtype recombinants
Author: Vazquez-García, J.A.
Shalisko, V.
Cuevas-Guzman, R.
Muniz-Castro, M.A.
Mantilla-Blandon, M.R.
Issue Date: 2014
Abstract: Recent morphological and phenological data support recognition of Abies jaliscana (Martínez) Mantilla, A. Vázquez & Shalisko at the species level. A key to distinguish A. jaliscana from other species of Abies in western Mexico is provided. " 2014 Magnolia Press.",,,,,,"10.11646/phytotaxa.183.1.3",,,"http://hdl.handle.net/20.500.12104/39168","http://www.scopus.com/inward/record.url?eid=2-s2.0-84907967439&partnerID=40&md5=adf23313ea3abb392641ebcd2d0006d1",,,,,,"1",,"Phytotaxa",,"27
36",,"183",,"Scopus
WOS",,,,,,"Abies durangensis; Abies flinckii; Abies guatemalensis; Abies religiosa; Jalisco; Sierra de Cacoma; Sierra de Cuale",,,,,,"Abies jaliscana (Pinaceae): A new combination in section Grandis and a key to the species of Abies in western Mexico",,"Article" "44698","123456789/35008",,"Vázquez-Valls, E., UMAE de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano Del Seguro Social, Guadalajara, Mexico, Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro Social, Guadalajara, Mexico; Escoto-Delgadillo, M., Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Guadalajara, Mexico; López-Márquez, F.C., Departamento de Inmunobiología Molecular, Del Centro de Investigación Biomédica, De la Facultad de Medicina de la Universidad Autónoma de Torreón, Torreón, Mexico; Castillero-Manzano, M., UMAE de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano Del Seguro Social, Guadalajara, Mexico; Echegaray-Guerrero, E., UMAE de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano Del Seguro Social, Guadalajara, Mexico; Bitzer-Quintero, O.K., Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro Social, Guadalajara, Mexico; Kobayashi-Gutiérrez, A., Hospital Civil de Guadalajara, Secretaría de Salud, Guadalajara, Mexico; Torres-Mendoza, B.M., Centro de Investigación Biomédica de Occidente, Instituto Mexicano Del Seguro Social, Guadalajara, Mexico, Departamento de Clínicas Médicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico",,"Vazquez-Valls, E.
Escoto-Delgadillo, M.
Lopez-Marquez, F.C.
Castillero-Manzano, M.
Echegaray-Guerrero, E.
Bitzer-Quintero, O.K.
Kobayashi-Gutierrez, A.
Torres-Mendoza, B.M.",,"2010",,"The molecular epidemiology of subtypes and intersubtype recombinants (IRs) of human immunodeficiency virus type 1 (HIV-1) in Mexico has not been characterized fully. Understanding its regional distribution, prevalence, adaptability, viral fitness, pathogenicity, and immunogenicity is decisive for any design of an effective HIV vaccine. The aim of this study was to describe the presence of IRs types BG and BF in a Mexican population. Protease and reverse transcriptase regions of the pol gene were sequenced using an automated sequencing system. A phylogenic tree was constructed and genetic distances were calculated using MEGA 3.1. Recombination analysis was done by bootscan using SimPlot software. Two hundred and twenty-three HIV-1-positive individuals were enrolled in the study. At baseline, the mean plasma viral load was 285,500 HIV-1 RNA copies/ml and the mean CD4 cell count was 213cells/ml. Subtype B was found in 220 (98.6%) samples, whereas IRs were found in three patients (1.4%): two (0.9%) with BG and one (0.45%) with BF. IRs were observed in 2/124 (1.6%) samples from treated patients and in 1/99 (1.0%) from naive patients. The presence of these HIV forms at low frequency points to the need for research on the diversity, geographic distribution, and evolution of other subtypes including circulating recombinant forms and IRs to understand the molecular epidemiology and tendencies of the HIV infection in Mexico. " Copyright 2010, Mary Ann Liebert, Inc.
URI: http://hdl.handle.net/20.500.12104/42919
http://www.scopus.com/inward/record.url?eid=2-s2.0-77954897634&partnerID=40&md5=b812437c53c34f72a7402f2013e9461d
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