Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/68688
Title: Y-SNP haplogroups related to the Yqh+ heteromorphism in the Mexican northwestern population
Author: Romo-Martinez, E.J.
Martinez-Cortes, G.
Barajas-Torres, R.L.
Rubi-Castellanos, R.
Magana-Torres, M.T.
Rangel-Villalobos, H.
Gonzalez-Garcia, J.R.
Issue Date: 2012
Abstract: Morphological variation of the Y chromosome has been observed in different populations. This variation is mostly related to the heteromorphic Yq12 band, which is composed of a variable block of constitutive heterochromatin. The Yqh+ heteromorphism has a worldwide frequency of 2.85% and is considered clinically innocuous. The aim of this study was to identify the ancestry of the Yqh+ heteromorphism present in individuals from western Mexico. For this purpose, 17 Y-chromosome single nucleotide polymorphisms were analysed by multiplex polymerase chain reaction and SNaPshot assays. In 28 Yqh+ males, only five haplogroups were observed; with a haplogroup diversity of 0.4841 ± 0.1094, which was less than that observed in a study of unselected Mexican mestizo population. Differences were specifically conferred by the high frequencies of haplogroups R1b1 and P*(xQ,R), and by the absence of the Amerindian haplogroup Q (Q*(xQ1a3a) plus Q1a3a) from the Yqh+ group. This study suggests a post-1492 incorporation for Yqh+ chromosomes into the Mexican northwestern population. © 2012 Indian Academy of Sciences.
URI: http://hdl.handle.net/20.500.12104/68688
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