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|Title:||T-helper 17-related cytokines and IgE antibodies during hepatitis A virus infection in children|
|Abstract:||We determined the serum IgE levels and T-helper (Th)17-related cytokines during distinct hepatitis A virus (HAV)-induced clinical courses in children. A significantly higher concentration of macrophage inflammatory protein 3α, interleukin (IL)-17E and IL-17F in HAV-infected children with intermediate liver injury compared with those with minor liver damage was found. A reduction in the IgE levels in those patients who showed the highest levels of IL-17F in the group of intermediate liver injury was found. The data suggested that the Th17-related profile is associated with the severity of HAV infection and might play a role on the modulation achieved by HAV during allergies. © 2015, Fundacao Oswaldo Cruz. All rights reserved.|
|Appears in Collections:||Producción científica UdeG (prueba)|
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