Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/68244
Title: T-helper 17-related cytokines and IgE antibodies during hepatitis A virus infection in children
Author: Trujillo-Ochoa, J.L.
Corral-Jara, K.F.
Escobedo-Melendez, G.
Realpe, M.
Panduro-Cerda, Arturo
Roman, S.
Fierro, N.A.
Issue Date: 2015
Abstract: We determined the serum IgE levels and T-helper (Th)17-related cytokines during distinct hepatitis A virus (HAV)-induced clinical courses in children. A significantly higher concentration of macrophage inflammatory protein 3α, interleukin (IL)-17E and IL-17F in HAV-infected children with intermediate liver injury compared with those with minor liver damage was found. A reduction in the IgE levels in those patients who showed the highest levels of IL-17F in the group of intermediate liver injury was found. The data suggested that the Th17-related profile is associated with the severity of HAV infection and might play a role on the modulation achieved by HAV during allergies. © 2015, Fundacao Oswaldo Cruz. All rights reserved.
URI: http://hdl.handle.net/20.500.12104/68244
Appears in Collections:Producción científica UdeG (prueba)

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