Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/67237
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dc.contributor.authorEscobedo-Melendez, G.
dc.contributor.authorFierro, N.A.
dc.contributor.authorRoman, S.
dc.contributor.authorMaldonado-Gonzalez, M.
dc.contributor.authorZepeda-Carrillo, E.
dc.contributor.authorPanduro-Cerda, Arturo
dc.date.accessioned2015-11-19T18:52:00Z-
dc.date.available2015-11-19T18:52:00Z-
dc.date.issued2012
dc.identifier.urihttp://hdl.handle.net/20.500.12104/67237-
dc.description.abstractIntroduction. Viral hepatitis in children is a major public health problem worldwide. Aim. To evaluate the prevalence of serological markers for hepatitis A, B and C infections in Mexican children diagnosed with hepatitis during a five-year period. Material and methods. A total of 31,818 children admitted to a tertiary level hospital in Mexico from 2005 to 2009 were evaluated for hepatitis. Results. Hepatitis was found in 215 (0.7%) of the children. Serum samples from hepatitis-positive children were screened for anti-HAV IgM, HBsAg, total anti-HBc and anti-HCV. HAV was the leading cause of viral hepatitis (81%), followed by HBV and HCV (3.1 and 2%, respectively), whereas no serological marker was observed in 13.9% of the analyzed samples. Furthermore, when children were categorized by age, a significant increase in anti-HAV detection was observed in school-aged children (7-11 years old) (p < 0.001) and a reduction in adolescents (12-15 years old). Conclusion. In conclusion, hepatitis A is the most prevalent viral hepatitis infection detected in children, followed by HBV and HCV. In addition, the high percentage of hepatitis infections without a known etiological agent and the serological test limitations require the detection of occult HBV, HCV and hepatitis E infections. The age-dependent vulnerability of groups with HAV infections emphasizes the importance of HAV vaccination in young children in Mexico.
dc.titlePrevalence of hepatitis A, B and C serological markers in children from western Mexico
dc.typeArticle
dc.relation.ispartofjournalAnnals of Hepatology
dc.relation.ispartofvolume11
dc.relation.ispartofissue2
dc.relation.ispartofpage194
dc.relation.ispartofpage201
dc.subject.keywordHepatitis A virus; Hepatitis B virus; Hepatitis C virus; Mexican children
dc.contributor.affiliationEscobedo-Meléndez, G., Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico, Department of Pediatric Infectious Disease, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico; Fierro, N.A., Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico; Roman, S., Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico; Maldonado-González, M., Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico; Zepeda-Carrillo, E., Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico; Panduro, A., Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde, University of Guadalajara, Guadalajara, Jalisco, Mexico
dc.contributor.affiliationPanduro-Cerda, Arturo., Universidad de Guadalajara
dc.subject.headingIndex Medicus;Adolescent;Child;Child, Preschool;Female;Hepatitis A/ep [Epidemiology];Hepatitis A Antibodies/bl [Blood];Hepatitis A Antibodies/im [Immunology];Hepatitis B/ep [Epidemiology];Hepatitis B Antibodies/bl [Blood];Hepatitis B Antibodies/im [Immunology];Hepatitis B Surface Antigens/bl [Blood];Hepatitis B Surface Antigens/im [Immunology];Hepatitis C/ep [Epidemiology];Hepatitis C Antibodies/bl [Blood];Hepatitis C Antibodies/im [Immunology];Hepatitis, Viral, Human/bl [Blood];Hepatitis, Viral, Human/ep [Epidemiology];Hospitalization;Humans;Infant;Infant, Newborn;Male;Mexico/ep [Epidemiology];Postoperative Complications;Risk Factors;Sanitation;Seroepidemiologic Studies
dc.relation.isReferencedByScopus
dc.relation.isReferencedByMEDLINE
dc.relation.isReferencedByWOS
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84856906571&partnerID=40&md5=8d236d0a47348e4f39f0793afd7bf787
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=22345336
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