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|Title:||Towards a Systematic Service-oriented Requirements Engineering process (S-SoRE)|
|Abstract:||Postcholecystectomy bile duct injuries (BDI) produce hepatic cholestasis and cause infection of the biliary tract. The biliary cells participate in secreting cytokines and in expression of immune response receptors. Toll-like receptors (TLRs) conduct signalling and activate the innate and adaptive inflammatory response. The objective was to determine the serum levels of TLR-2 and the expression of TLR-1 and TLR-2 and ?-defensin in liver biopsies of postcholecystectomy BDI patients. A transverse, analytical study with 2 groups was done. One group included healthy volunteers (control group) and other included 25 postcholecystectomy BDI patients with complete biliary obstruction. Using the Enzyme-linked Immunosorbent Assay (ELISA) technique, serum levels of TLR-2 were determined, and with immunofluorescence the morphologic analysis of TLR-1 and TLR-2 and ?-defensin in liver biopsies of postcholecystectomy BDI patients was performed. The average TLR-2 serum level in the control group was 0.0 pg/mL and in the BDI group, 0.023 0.0045 pg/mL (P<0.0001, bilateral Mann Whitney U). Immunofluorescence was used to determine the expression in liver biopsies, blood vessels, bile ducts, and hepatic parenchyma where 12 hepatic biopsies were positive for TLR-1 with average of 3213057.74 1071019.25 ?m2; and 7 biopsies were positive for ?-defensin with an average of 730364.33 210838.02 ?m2; and 6 biopsies positive for TLR-2, obtaining an average of 3354364.24 838591.06 ?m2. In conclusion, TLR-1 and TLR-2 and ?-defensin play an important role in the innate antimicrobial defense of the hepatobiliary system. " 2015 Alejandra Guillermina Miranda-Díaz et al.",,,,,,"10.1155/2015/216129",,,"http://hdl.handle.net/20.500.12104/45387","http://www.scopus.com/inward/record.url?eid=2-s2.0-84924213349&partnerID=40&md5=956d52d45d8b02d8b1ee70c24c4a5289|
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25755667",,,,,,,,"Gastroenterology Research and Practice",,,,"2015",,"Scopus
MEDLINE",,,,,,,,,,,,"Toll-like receptor-1 and receptor-2 and beta-defensin in postcholecystectomy bile duct injury",,"Article" "47186","123456789/35008",,"Flores, F., Computer Science Department, Autonomous University of Aguascalientes, Aguascalientes, Ags., 20131, Mexico; Mora, M., Information Systems Department, Autonomous University of Aguascalientes, Aguascalientes, Ags., 20131, Mexico; Álvarez, F., Computer Science Department, Autonomous University of Aguascalientes, Aguascalientes, Ags., 20131, Mexico; Garza, L., Information Systems Department, Autonomous University of Aguascalientes, Aguascalientes, Ags., 20131, Mexico; Durán, H., Computer Science Department, University of Guadalajara, Guadalajara, 44130, Mexico",,"Flores, F.
Duran, H.",,"2010",,"Software and System Requirements Engineering (RE) is considered a critical process for successful projects. Incomplete, ambiguous, and/or wrong requirements can be delivered for next design phase when this process is non-adequately performed. Thus, a well-defined and suitable RE process is needed. For usual computing paradigms (e.g. object-oriented and component-based schemes) several stable RE processes are available. However, under the emergent service-oriented computing paradigm, while diverse adaptations have been posed, none of them has gained yet their standardized utilization acknowledgment. Consequently, academics and practitioners are still confused on what RE process and specific techniques can be used for developing service-oriented software systems (SoSS). In this paper, for advancing on such a problem and through a conceptual design research, we report: (i) an overview of a classic RE process and main used techniques, (ii) an analysis of emergent techniques reported in other domains but useful for SoSS RE, and (iii) an initial 30-mile view of a proposed systematic service-oriented requirements engineering (S-SoRE) process. " 2010 Springer-Verlag.
|Appears in Collections:||Producción científica UdeG|
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