Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/43516
Title: Labeling of HeLa cells using ZrO<inf>2</inf>:Yb3+-Er3+ nanoparticles with upconversion emission
Author: Gutierrez-Amavizca, B.E.
Orozco-Castellanos, R.
Padilla-Gutierrez, J.R.
Valle, Y.
Figuera, L.E.
Issue Date: 2014
Abstract: Fabry disease (FD) is an X-linked lysosomal storage disease caused by ?-galactosidase A deficiency; in contrast to other X-linked diseases, heterozygous females can be as affected as men. The construction and analysis of a family pedigree is a powerful tool to aid clinicians in diagnosis, establishment of inheritance pattern, and early detection of potentially affected relatives. The present study highlights the importance of pedigree analysis in families with FD for identifying other possibly affected relatives and investigating the clinical manifestations. This clinical report included 12 Mexican index cases with confirmed FD diagnosis. We constructed and analyzed their pedigree, and diagnosed FD in 24 affected relatives. Clinical features were similar to those reported for other populations. Pedigree analysis further identified an additional 30 women as possible carriers. We conclude that pedigree construction and analysis is a useful tool to help physicians detect and diagnose relatives at risk for FD, particularly heterozygous females, so that they can receive genetic counseling and early treatment. Mexican families with FD were similar to other populations reported in the literature, and our findings confirmed that heterozygous females can have signs and symptoms ranging from subtle manifestations to the classical severe presentation described in males. " FUNPEC-RP.",,,,,,"10.4238/2014.August.28.19",,,"http://hdl.handle.net/20.500.12104/43516","http://www.scopus.com/inward/record.url?eid=2-s2.0-84907153993&partnerID=40&md5=f5e6b77784306b3b4121f8b1b60ffc2f
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25177955",,,,,,"3",,"Genetics and Molecular Research",,"6752
6758",,"13",,"Scopus
MEDLINE
WOS",,,,,,"Fabry disease; Female carrier; Heterozygous; Lysosomal storage disease; Pedigree; X-linked",,,,,,"Pedigree analysis of Mexican families with Fabry disease as a powerful tool for identification of heterozygous females",,"Article" "44253","123456789/35008",,"Jesús Salvador, V.-F., Centro de Medicina Genómica del Hospital General de, Culiacan Dr. Bernardo J. Gastelum, Servicios de Salud de Sinaloa. Culiacán Sinaloa, México and Facultad de Medicina Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, Mexico; José Guadalupe, R.-M., Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, Mexico; Luis Antonio, O.-R., Maestría en Inmunología, Facultad Ciencias Biológicas, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico; Héctor, R.-V., Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Ocotlán, Jalisco, Mexico",,"Jesus Salvador, V.-F.
Jose Guadalupe, R.-M.
Luis Antonio, O.-R.
Hector, R.-V.",,"2012",,"[No abstract available]",,,,,,"10.1111/j.1365-4632.2010.04597.x",,,"http://hdl.handle.net/20.500.12104/42474","http://www.scopus.com/inward/record.url?eid=2-s2.0-84862676786&partnerID=40&md5=0c9b0bc7e2ed4bbe16168f82bd7de936",,,,,,"7",,"International Journal of Dermatology",,"875
876",,"51",,"Scopus
WOS",,,,,,,,,,,,"Lack of association between 3? UTR 1188 A/C polymorphism in the IL-12p40 gene and lepromatous leprosy in Sinaloa, Mexico",,"Letter" "44245","123456789/35008",,"Ceja-Fdez, A., Centro de Investigaciones en óptica, A.C., Loma del Bosque 115Lomas del Campestre, CP, León, Guanajuato, Mexico; López-Luke, T., Centro de Investigaciones en óptica, A.C., Loma del Bosque 115Lomas del Campestre, CP, León, Guanajuato, Mexico; Oliva, J., Centro de Investigaciones en óptica, A.C., Loma del Bosque 115Lomas del Campestre, CP, León, Guanajuato, Mexico; Vivero-Escoto, J., University of North Carolina at Charlotte, Department of Chemistry, 9201 University City BoulevardCharlotte, NC, United States; Gonzalez-Yebra, A.L., Universidad de Guanajuato Campus León, Departamento de Medicina y Nutrición, División Ciencias de la Salud, Boulevard Puente Milenio 1001Predio San Carlos, CP, León, Guanajuato, Mexico; Rojas, R.A.R., Universidad de Guadalajara, Centro Universitario de Los Lagos, Paseos de la MontañaCP, Lagos de Moreno, Jalisco, Mexico; Martínez-Pérez, A., Centro de Investigaciones en óptica, A.C., Loma del Bosque 115Lomas del Campestre, CP, León, Guanajuato, Mexico, Universidad de Guadalajara, Centro Universitario de Los Lagos, Paseos de la MontañaCP, Lagos de Moreno, Jalisco, Mexico; De La Rosa, E., Centro de Investigaciones en óptica, A.C., Loma del Bosque 115Lomas del Campestre, CP, León, Guanajuato, Mexico",,"Ceja-Fdez, A.
Lopez-Luke, T.
Oliva, J.
Vivero-Escoto, J.
Gonzalez-Yebra, A.L.
Rojas, R.A.R.
Martinez-Perez, A.
De La Rosa, E.",,"2015",,"This work reports the synthesis, structural characterization, and optical properties of ZrO<inf>2</inf>:Yb3+-Er3+ (2-1 mol%) nanocrystals. The nanoparticles were coated with 3-aminopropyl triethoxysilane (APTES) and further modified with biomolecules, such as Biotin-Anti-rabbit (mouse IgG) and rabbit antibody-AntiKi-67, through a conjugation method. The conjugation was successfully confirmed by Fourier transform infrared, zeta potential, and dynamic light scattering. The internalization of the conjugated nanoparticles in human cervical cancer (HeLa) cells was followed by two-photon confocal microscopy. The ZrO<inf>2</inf>:Yb3+-Er3+ nanocrystals exhibited strong red emission under 970-nm excitation. Moreover, the luminescence change due to the addition of APTES molecules and biomolecules on the nanocrystals was also studied. These results demonstrate that ZrO<inf>2</inf>:Yb3+-Er3+ nanocrystals can be successfully functionalized with biomolecules to develop platforms for biolabeling and bioimaging. " The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.
URI: http://hdl.handle.net/20.500.12104/42466
http://www.scopus.com/inward/record.url?eid=2-s2.0-84928390600&partnerID=40&md5=758f737488319c85fc694bd89ed3a781
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=prem&AN=25879389
Appears in Collections:Producción científica UdeG

Files in This Item:
There are no files associated with this item.


Items in RIUdeG are protected by copyright, with all rights reserved, unless otherwise indicated.