Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/41172
Title: National prevalence and trends of hiv transmitted drug resistance in mexico
Author: Torres-Jasso, J.H.
Marin, M.E.
Luna Santiago, E.S.
Leoner, J.C.
Torres, J.
Magana-Torres, M.T.
Perea, F.J.
Ibarra, B.
Sanchez-Lopez, J.Y.
Issue Date: 2015
Abstract: Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with tyrosine-kinase activity that plays an important role in multiple cellular functions. EGFR overexpression has been observed in several types of tumors and it is significantly associated with disease stage, survival, prognosis, and progression of cancer. The polymorphisms -216G>T, -191C>A, and (CA)n first intervening sequence (IVS1) have been related to EGFR overexpression and have been studied in several types of cancer, but not in gastric cancer (GC). The aim of this study was to determine the association of these 3 polymorphisms and GC. Genomic DNA from 68 GC patients and 102 healthy blood donors were analyzed. Polymorphisms were identified by DNA-sequencing (-216G>T and -191C>A) and GeneScan (CA)n IVS1. The results showed that the distribution of the -216G>T and -191C>A genotypes differed between groups (P < 0.05). The odds ratio for the -216TT genotype was 4.59 (95% confidence interval = 1.55-13.54, P < 0.05) and 10.71 (95% confidence interval = 2.31-49.59, P < 0.05) for the -191AA genotype, both in a recessive model. The genotype and allele distributions of the (CA)n IVS1 repeat was similar in both groups. In conclusion, the -216TT and -191AA genotypes and GA haplotype of the EGFR gene were found to be associated with an increased risk of gastric cancer in a Mexican population. "FUNPEC-RP.",,,,,,"10.4238/2015.March.13.8",,,"http://hdl.handle.net/20.500.12104/41172","http://www.scopus.com/inward/record.url?eid=2-s2.0-84924794911&partnerID=40&md5=a67558f3b3ac4b31a53a1eed2cfeafd9",,,,,,"1",,"Genetics and Molecular Research",,"1802
1807",,"14",,"Scopus",,,,,,"EGFR; ERBB1; Gastric cancer; Polymorphism",,,,,,"EGFR gene polymorphisms -216G>T and -191C>A are risk markers for gastric cancer in Mexican population",,"Article" "42952","123456789/35008",,"Virla, E.G., PROIMI-Biotecnología, Div. Control Biológico, Av. Belgrano y Pje. Caseros (T4001 MVB), San Miguel de Tucumán, Tucumán, Argentina; Albarracin, E.L., PROIMI-Biotecnología, Div. Control Biológico, Av. Belgrano y Pje. Caseros (T4001 MVB), San Miguel de Tucumán, Tucumán, Argentina; Moya-Raygoza, G., Departamento de Botánica y Zoología, CUCBA, Universidad de Guadalajara, km 15.5 carretera Guadalajara-Nogales, Zapopan, C.P. 45110, Jalisco, Mexico",,"Virla, E.G.
Albarracin, E.L.
Moya-Raygoza, G.",,"2009",,"A survey of eggs parasitoids of the corn leafhopper, Dalbulus maidis (DeLong & Wolcott) was conducted in Jalisco State, Mexico. Samples were collected during the summer of 2008 with sentinel eggs. Five taxa, Anagrus breviphragma Soyka and Polynema sp. (Mymaridae), Paracentrobia nr subflava, Aphelinoidea sp., and Pseudoligosita sp. (Trichogrammatidae) were reared. This is the first reference to an egg parasitoid complex of the corn leafhopper in Mexico, and A. breviphragma is recorded for the first time occurring in Mexico.",,,,,,"10.1653/024.092.0316",,,"http://hdl.handle.net/20.500.12104/41173","http://www.scopus.com/inward/record.url?eid=2-s2.0-70349504831&partnerID=40&md5=533cc863390fe9fae4b2cd145b968915
http://dx.doi.org/10.1653/024.092.0316",,,,,,"3",,"Florida Entomologist",,"508
510",,"92",,"Scopus
WOS
BioOne",,,,,,,,,,,,"Egg parasitoids of dalbulus maidis (Hemiptera: Cicadellidae) in jalisco state, Mexico",,"Article" "41799","123456789/35008",,"Delgado, F.Ezequiel, Universidad de Guadalajara, Jalisco, Mexico; Lopez-Dellamary, Fernando A., Universidad de Guadalajara, Jalisco, Mexico; Allan, G.G., Universidad de Guadalajara, Jalisco, Mexico; Cresson, T., Universidad de Guadalajara, Jalisco, Mexico",,"Delgado, F.Ezequiel
Lopez-Dellamary Fernando, A.
Allan, G.G.
Cresson, T.",,"1997",,"The modification of cellulose surfaces with zwitterions (here exemplified by amino acids) was investigated. The purpose of the modification was to affect bonding between cellulosic surfaces by the creation of new type of bonds (zwitterionic) and/or enhancing their normal capability to form hydrogen bonds. Paper made from zwitterionic fibers retained more than 30% of their dry strength after being saturated with water. Measurements of the strength of never-dried zwitterionic paper webs indicated that the introduction of zwitterions onto the fibers produced stronger webs at solids content above 55%.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40020","http://www.scopus.com/inward/record.url?eid=2-s2.0-17644445084&partnerID=40&md5=d2a5d8dce7b90d51aa63bfe18ac7a610",,,,,,,,"Proceedings of the ACM Workshop on Role-Based Access Control",,"O2
1-O2-4",,"1",,"Scopus",,,,,,,,,,,,"Chemical modification of fibers: Its potential for obtaining wet strength in paper",,"Conference Paper" "44810","123456789/35008",,"Avila-Ríos, S., Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico; García-Morales, C., Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico; Garrido-Rodríguez, D., Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico; Ormsby, C.E., Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico; Hernández-Juan, R., Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico; Andrade-Villanueva, J., Unidad de VIH/SIDA, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico; González-Hernández, L.A., Unidad de VIH/SIDA, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico; Torres-Escobar, I., Hospital General de Puebla, Puebla, Puebla, Mexico, Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, Puebla, Puebla, Mexico; Navarro-Álvarez, S., Hospital General de Tijuana, Tijuana, Baja California, Mexico; Reyes-Terán, G., Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico",,"Avila-Rios, S.
García-Morales, C.
Garrido-Rodriguez, D.
Ormsby, C.E.
Hernandez-Juan, R.
Andrade-Villanueva, J.
Gonzalez-Hernandez, L.A.
Torres-Escobar, I.
Navarro-Alvarez, S.
Reyes-Teran, G.",,"2011",,"Background: Transmitted drug resistance (TDR) remains an important concern for the management of HIV infection, especially in countries that have recently scaled-up antiretroviral treatment (ART) access. Methodology/Principal Findings: We designed a study to assess HIV diversity and transmitted drug resistance (TDR) prevalence and trends in Mexico. 1655 ART-naive patients from 12 Mexican states were enrolled from 2005 to 2010. TDR was assessed from plasma HIV pol sequences using Stanford scores and the WHO TDR surveillance mutation list. TDR prevalence fluctuations over back-projected dates of infection were tested. HIV subtype B was highly prevalent in Mexico (99.9%). TDR prevalence (Stanford score&15) in the country for the study period was 7.4% (95% CI, 6.2:8.8) and 6.8% (95% CI, 5.7:8.2) based on the WHO TDR surveillance mutation list. NRTI TDR was the highest (4.2%), followed by NNRTI (2.5%) and PI (1.7%) TDR. Increasing trends for NNRTI (p = 0.0456) and PI (p = 0.0061) major TDR mutations were observed at the national level. Clustering of viruses containing minor TDR mutations was observed with some apparent transmission pairs and geographical effects. Conclusions: TDR prevalence in Mexico remains at the intermediate level and is slightly lower than that observed in industrialized countries. Whether regional variations in TDR trends are associated with differences in antiretroviral drug usage/ART efficacy or with local features of viral evolution remains to be further addressed. " 2011 Avila-Ríos et al.
URI: http://hdl.handle.net/20.500.12104/43031
http://www.scopus.com/inward/record.url?eid=2-s2.0-84858771311&partnerID=40&md5=47543273f097c0c35af8de383bf9335c
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