Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12104/40645
Title: Diffuse reflectance spectroscopy and Optical polarization imaging of in-vivo biological tissue
Author: Medina-Ceja, L.
Ventura-Mejia, C.
Issue Date: 2010
Abstract: In vivo and in vitro evidence from animals suggesting that gap junctions (GJs) play a role in the spreading of epileptiform activity. We have examined the influence of the gap junction opener trimethylamine (TMA) and the connexin 36 (Cx36) gap junctional blocker, quinine, on epileptiform activity induced by 4-aminopyridine (4-AP) in the rat entorhinal cortex (EC) and the CA1 hippocampal region. A cannula and surface electrodes were implanted into the brain to administer drugs and to monitor electrical activity. Injection of 4-AP (10 nmol) produced epileptiform discharge trains of high amplitude and frequency associated with seizure behavior rated between 0 and 3 in the Racine scale. In the presence of TMA (500 nmol), 4-AP produced distinct epileptiform patterns with continuous, long epileptiform discharges of high amplitude and frequency associated with seizure behavior of 0, 1, 3 and 5 during the first 30 min post-drug administration that diminished after 90 min. Quinine injection (35 pmol) into the EC of seizing animals decreased the amplitude and frequency of the discharge trains in the EC and CA1 regions, which were completely blocked after 34 min. Indeed, the seizure behavior of the animals was completely blocked in five of the six rats 53.2 s after quinine administration. We suggest that the intensity of the proepileptic effect of TMA on epileptiform activity depends on the time and route of drug administration, and that neural Cx36-dependent GJs are important structures in the generation of epileptiform activity, as well as in the seizure behavior induced by 4-AP. " 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.",,,,,,"10.1016/j.seizure.2010.07.009",,,"http://hdl.handle.net/20.500.12104/40645","http://www.scopus.com/inward/record.url?eid=2-s2.0-77957264564&partnerID=40&md5=5d368f7336f2f283e2b0646a3228e35c
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=med5&AN=20685138",,,,,,"8",,"Seizure",,"507
513",,"19",,"Scopus
MEDLINE
WOS",,,,"Index Medicus;4-Aminopyridine;Animals;Azides;Behavior, Animal/de [Drug Effects];CA1 Region, Hippocampal/de [Drug Effects];CA1 Region, Hippocampal/pp [Physiopathology];Entorhinal Cortex/de [Drug Effects];Entorhinal Cortex/pp [Physiopathology];Epilepsy/ci [Chemically Induced];Epilepsy/dt [Drug Therapy];Epilepsy/pp [Physiopathology];Gap Junctions/de [Drug Effects];Male;Methylamines/pd [Pharmacology];Octreotide/aa [Analogs & Derivatives];Potassium Channel Blockers;Quinine/pd [Pharmacology];Rats;Rats, Wistar;Wakefulness",,"4-AP; Connexin 36; Entorhinal cortex; Quinine; Seizures; Trimethylamine",,,,,,"Differential effects of trimethylamine and quinine on seizures induced by 4-aminopyridine administration in the entorhinal cortex of vigilant rats",,"Article" "42432","123456789/35008",,"Olivares, J., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Allen, C., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Sánchez, L.J., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Ruelas-Mayorga, A., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Poveda, A., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Costero, R., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Nigoche-Netro, A., Instituto de Astronomía y Meteorología, Universidad de GuadalajaraGuadalajara, Jalisco, Mexico",,"Olivares, J.
Allen, C.
Sanchez, L.J.
Ruelas-Mayorga, A.
Poveda, A.
Costero, R.
Nigoche-Netro, A.",,"2014",,"Using the historical database of the Washington Double Star Catalog (WDS) and astrometric data obtained by applying the Diffracto-Astrometry (DiAs) technique to Hubble Space Telescope Wide Field Planetary Camera 2 (HST/WFPC2) public images, the relative kinematics of the Orion Trapezium (OT) stellar components is obtained with a precision of ?1 km s-1.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40653","http://www.scopus.com/inward/record.url?eid=2-s2.0-84922264077&partnerID=40&md5=7bf3562ac8f7ec1e10cd834b8b93dbd2",,,,,,,,"Revista Mexicana de Astronomia y Astrofisica: Serie de Conferencias",,"83
84",,"43",,"Scopus",,,,,,"Astrometry; Open clusters and associations: general; Stars: kinematics and dynamics",,,,,,"Diffracto-astrometry measurements: Kinematics of the orion trapezium",,"Conference Paper" "42433","123456789/35008",,"Sánchez, L.J., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Ruelas-Mayorga, A., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Olivares, J., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Allen, C., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Poveda, A., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Costero, R., Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. Postal 70-264México, D.F., Mexico; Nigoche-Netro, A., Instituto de Astronomía y Meteorología, Universidad de GuadalajaraGuadalajara, Jalisco, Mexico",,"Sanchez, L.J.
Ruelas-Mayorga, A.
Olivares, J.
Allen, C.
Poveda, A.
Costero, R.
Nigoche-Netro, A.",,"2014",,"We investigate the possibility of performing precision astrometry on saturated stellar images of the Hubble Space Telescope (HST) Wide Field Planetary Camera 2 (WFPC2). We obtain the position of the stellar photocentres by using a centring technique which utilises the diffraction pattern produced by the secondary mirror support. This technique appears to be very promising in the astrometrical analysis. It allows a precision of the order of 10 milliarcseconds in WFPC2 images.",,,,,,,,,"http://hdl.handle.net/20.500.12104/40654","http://www.scopus.com/inward/record.url?eid=2-s2.0-84922214690&partnerID=40&md5=dc46cfdca650b19ac5c87acc8b963675",,,,,,,,"Revista Mexicana de Astronomia y Astrofisica: Serie de Conferencias",,"75
76",,"43",,"Scopus",,,,,,"Methods: data analysis; Techniques: image processing",,,,,,"Diffracto-astrometry measurements: The technique",,"Conference Paper" "42434","123456789/35008",,"Mora-Núñez, A., Departamento de Electrónica, Universidad de Guadalajara, Av. Revolución 1500, 44430 Guadalajara, Jal., Mexico; Castillejos, Y., Centro de Investigaciones en óptica, Apdo. Postal 1-948, 37000 León-Gto., Mexico; García-Torales, G., Departamento de Electrónica, Universidad de Guadalajara, Av. Revolución 1500, 44430 Guadalajara, Jal., Mexico; Martínez-Ponce, G., Centro de Investigaciones en óptica, Apdo. Postal 1-948, 37000 León-Gto., Mexico",,"Mora-Nunez, A.
Castillejos, Y.
García-Torales, G.
Martinez-Ponce, G.",,"2013",,"A number of optical techniques have been reported in the scientific literature as accomplishable methodologies to diagnose diseases in biological tissue, for instance, diffuse reflectance spectroscopy (DRS) and optical polarization imaging (OPI). The skin is the largest organ in the body and consists of three primary layers, namely, the epidermis (the outermost layer exposed to the world), the dermis, and the hypodermis. The epidermis changes from to site to site, mainly because of difference in hydration. A lower water content increase light scattering and reduce the penetration depth of radiation. In this work, two hairless mice have been selected to evaluate their skin features by using DRS and OPI. Four areas of the specimen body were chosen to realize the comparison: back, abdomen, tail, and head. From DRS, it was possible to distinguish the skin nature because of different blood irrigation at dermis. In the other hand, OPI shows pseudo-depolarizing regions in the measured Mueller images related to a spatially varying propagation of the scattered light. This provides information about the cell size in the irradiated skin. " 2013 SPIE.
URI: http://hdl.handle.net/20.500.12104/40655
http://www.scopus.com/inward/record.url?eid=2-s2.0-84891304363&partnerID=40&md5=9a975c882e4a11356a3889d73e07f95a
Appears in Collections:Producción científica UdeG

Files in This Item:
There are no files associated with this item.


Items in RIUdeG are protected by copyright, with all rights reserved, unless otherwise indicated.